SCHEMBL168334

SCHEMBL168334

C=C(C(=O)O)C(CC)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 3/20 0.36
TET3 O43151 1/20 0.36
TET1 Q8NFU7 1/20 0.36
CHRM1 P11229 1/20 0.35
AKR1A1 P14550 1/20 0.35
CHRM3 P20309 1/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
ADRA1A P35348 1/20 0.35
HRH1 P35367 1/20 0.35
DRD3 P35462 1/20 0.35
SLC6A3 Q01959 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
GRIK1 P39086 1/20 0.34
GRIK2 Q13002 1/20 0.34
GRM1 Q13255 1/20 0.34
GRM2 Q14416 1/20 0.34
CA2 P00918 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1300073 0.85
SCHEMBL8852391 0.83 CA1 (0.34) TDP1GRIK1GRIK2GRM1GRM2
SCHEMBL1949300 0.80 TDP1 (0.38) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL1794769 0.80 CHRM1 (0.48) TET2CHRM1AKR1A1CHRM3HTR2A
SCHEMBL10952875 0.78 TDP1 (0.32) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL2408287 0.78
Ethylmalonate SCHEMBL28635933 0.77 HDAC1 (0.41) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL1259560 0.77 HDAC1 (0.44) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL577633 0.77 CA2 (0.48) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL5276347 0.77 ALDH1A1 (0.41) TET2CHRM1AKR1A1CHRM3HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118290652-A Novel bio-based ternary polymer and preparation method and application thereof 南京艾普拉斯化工有限公司 2024-07-05 CN claimed
US-20200375929-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF DISEASES ASSOCIATED WITH CANCER, INFLAMMATION, OR IMMUNE RESPONSE NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2020-12-03 US claimed
EP-3199560-B1 MODIFIED POLYVINYL ALCOHOL AND WATER-SOLUBLE FILM KURARAY CO (JP) 2020-11-11 EP claimed
EP-2459606-B1 HYBRID COPOLYMER COMPOSITIONS NOURYON CHEMICALS INT BV (NL) 2020-10-21 EP claimed
EP-3668497-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF DISEASES ASSOCIATED WITH CANCER, INFLAMMATION, OR IMMUNE RESPONSE Washington University (US) 2020-06-24 EP claimed
WO-2019036509-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF DISEASES ASSOCIATED WITH CANCER, INFLAMMATION, OR IMMUNE RESPONSE WASHINGTON UNIVERSITY (US) 2019-02-21 WO claimed
EP-1346957-B1 MULTIFONCTIONAL CALCIUM CARBONATE AND CALCIUM PHOSPATE SCALE INHIBITOR AKZO NOBEL CHEMICALS INT BV (NL) 2018-08-08 EP claimed
EP-2145921-B1 Vulcanizable polymer compositions ARLANXEO DEUTSCHLAND GMBH (DE) 2017-01-25 EP claimed
US-9109068-B2 Hybrid copolymer compositions AKZO NOBEL N.V. (NL) 2015-08-18 US claimed
EP-2199326-B1 Vulcanizable polymer compositions LANXESS DEUTSCHLAND GMBH (DE) 2014-10-29 EP claimed
EP-2459606-A1 HYBRID COPOLYMER COMPOSITIONS Akzo Nobel N.V. (NL) 2012-06-06 EP claimed
US-20120128608-A1 Hybrid copolymer compositions AKZO NOBEL N.V. (NL) 2012-05-24 US claimed
WO-2011014783-A1 HYBRID COPOLYMER COMPOSITIONS AKZO NOBEL N.V. (NL) 2011-02-03 WO claimed
US-20110028371-A1 HYBRID COPOLYMERS AKZO NOBEL N.V. (NL) 2011-02-03 US claimed
EP-0397375-B1 Photosensitive composition and photosensitive lithographic printing plate KONISHIROKU PHOTO IND (JP) 1994-04-06 EP claimed
EP-0315478-B1 High-lubricity film KUREHA CHEMICAL IND CO LTD (JP) 1994-04-06 EP claimed
EP-0361769-B1 Thermoplastic elastomer composition and rubber parts of refrigerator having a layer composed of thermoplastic elastomer composition JAPAN SYNTHETIC RUBBER CO LTD (JP) 1994-03-30 EP claimed
EP-0238974-B1 HEAT RESISTANCE-IMPROVED METAL-POLYPROPYLENE LAMINATE COMPOSITE Chisso Corporation (JP) 1991-12-27 EP claimed
US-5021523-A Polymer alloy of polyarylene thioether and a process for producing the same KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1991-06-04 US claimed
EP-0397375-A1 Photosensitive composition and photosensitive lithographic printing plate KONICA CORPORATION (JP) 1990-11-14 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120128608-A1 Hybrid copolymer compositions EPHX2, PUF60, ELOVL6 TET2 2156/4885TET3 574/4885TET1 461/4885
US-20200375929-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF DISEASES ASSOCIATED WITH CANCER, INFLAMMATION, OR IMMUNE RESPONSE IKBKG, IKBKB, NFKBIA TET2 841/4885TET3 1706/4885TET1 1399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.