SCHEMBL17512466

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24131085	0.87	CYP1A2 (0.46)	CYP1A2LMNACYP3A4MAOAALDH1A1
	SCHEMBL8318161	0.85	ALDH1A1 (0.50)	CYP1A2LMNACYP3A4MAOAALDH1A1
	SCHEMBL25765775	0.83	KDM4E (0.46)	CYP1A2CYP3A4ALDH1A1KMT2AKDM4E
	SCHEMBL5820179	0.83	NPSR1 (0.42)	CYP3A4ALDH1A1KDM4EMAPK1L3MBTL1
	SCHEMBL5820404	0.83	GABRA1 (0.48)	CYP1A2LMNACYP3A4MAOAALDH1A1
	SCHEMBL15351111	0.81	CYP2C19 (0.54)	CYP1A2LMNACYP3A4MAOAALDH1A1
	SCHEMBL17986657	0.80	CYP1A2 (0.41)	CYP1A2LMNACYP3A4MAOAALDH1A1
	SCHEMBL22061414	0.80	MAPK1 (0.43)	CYP1A2CYP3A4ALDH1A1KMT2AKDM4E
	SCHEMBL4674787	0.80	OPRK1 (0.44)	ALDH1A1KMT2AMEN1KDM4EMAPK1
	SCHEMBL10269771	0.79	CYP2C19 (0.59)	CYP1A2LMNAALDH1A1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.