Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15758316 | 0.85 | NUDT1 (0.51) | BRD4CYP1A2LMNACYP3A4MAOA | |
| SCHEMBL14895438 | 0.85 | BRD4 (0.48) | BRD4CYP1A2LMNACYP3A4MAOA | |
| SCHEMBL25347956 | 0.85 | BRD4 (0.48) | BRD4CYP1A2LMNACYP3A4MAOA | |
| SCHEMBL28550577 | 0.84 | BRD4 (0.47) | BRD4CYP1A2LMNACYP3A4MAOA | |
| SCHEMBL21072556 | 0.83 | NOS3 (0.47) | ALDH1A1KDM4EHSD17B10HPGDNOS3 | |
| SCHEMBL27510506 | 0.83 | DPP4 (0.47) | BRD4CYP1A2LMNACYP3A4MAOA | |
| SCHEMBL6980662 | 0.82 | BRD4 (0.43) | BRD4CYP1A2LMNACYP3A4MAOA | |
| SCHEMBL7433335 | 0.81 | BRD4 (0.45) | BRD4CYP1A2LMNACYP3A4MAOA | |
| SCHEMBL9308847 | 0.81 | BRD4 (0.50) | BRD4CYP1A2LMNACYP3A4ALDH1A1 | |
| SCHEMBL7441626 | 0.80 | KDM4E (0.49) | BRD4CYP1A2LMNACYP3A4MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108883099-B | Thiazolidinone compounds and use thereof | 石全 | 2021-09-28 | — | — | CN | disclosed |