Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3231481 | 0.70 | TDO2 (0.58) | ALDH1A1GAAHPGDKDM4EGLA | |
| SCHEMBL4180431 | 0.70 | MAPT (0.45) | L3MBTL1ALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL4166906 | 0.67 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL7382934 | 0.59 | GABRA1 (0.58) | L3MBTL1ALDH1A1GAAHPGDKDM4E | |
| SCHEMBL1150847 | 0.59 | TSHR (0.75) | L3MBTL1ALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL25204733 | 0.59 | CNR1 (0.47) | ALDH1A1KMT2AMEN1TDO2 | |
| SCHEMBL1150574 | 0.59 | KMT2A (0.48) | L3MBTL1ALDH1A1KDM4EKMT2AMAPT | |
| SCHEMBL5623489 | 0.59 | LMNA (0.61) | ALDH1A1GAAHPGDKDM4EGLA | |
| SCHEMBL18425634 | 0.59 | HDAC1 (0.56) | ALDH1A1GAAHPGDLMNACRHBP | |
| SCHEMBL14697087 | 0.58 | USP2 (0.66) | L3MBTL1ALDH1A1KDM4ELMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011041512-A2 | COMPOSITIONS AND METHODS FOR TREATING MLV-INFECTION, AND PREVENTING AND TREATING MLV-INITIATED DISEASES | EMORY UNIVERSITY (US) | 2011-04-07 | — | — | WO | disclosed |