Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORB | Q92753 | 15/20 | 0.70 |
| ▸ | RORC | P51449 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10092890 | 0.84 | RORB (0.65) | RORBRORCCCNA2CDK2 | |
| SCHEMBL2492021 | 0.82 | RORB (0.69) | RORBRORCADORA1 | |
| SCHEMBL6258242 | 0.82 | RORB (0.69) | RORBRORCADORA1 | |
| SCHEMBL178204 | 0.81 | CDK5 (0.58) | RORBRORCCCNA2CDK2ADORA1 | |
| SCHEMBL257142 | 0.79 | RORB (1.00) | RORBRORC | |
| SCHEMBL168675 | 0.76 | RORB (0.46) | RORBRORCMAPT | |
| SCHEMBL11165291 | 0.76 | ALDH1A1 (0.69) | RORBRORCMAPT | |
| SCHEMBL257615 | 0.75 | RORB (0.72) | RORBRORCCCNA2CDK2 | |
| SCHEMBL14417425 | 0.74 | CCNA2 (0.48) | RORBCCNA2CDK2 | |
| SCHEMBL257436 | 0.74 | RORB (0.66) | RORBRORCMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027965-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-08 | — | — | WO | disclosed |