Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 15/20 | 0.64 |
| ▸ | F13A1 | P00488 | 5/20 | 0.60 |
| ▸ | TGM1 | P22735 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.60 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439369 | 0.84 | TGM2 (0.79) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL8315998 | 0.79 | TGM2 (0.39) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL81209 | 0.78 | TGM2 (1.00) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL995472 | 0.77 | TGM2 (0.61) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL133445 | 0.77 | TGM2 (0.68) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL28240522 | 0.77 | TGM2 (0.96) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL7270679 | 0.77 | TGM2 (0.68) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL30211836 | 0.77 | TGM2 (0.96) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL28703875 | 0.77 | TGM2 (0.68) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL25365033 | 0.76 | MTNR1A (0.47) | TGM2F13A1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113082220-B | pH-responsive surface charge reversal nano-carrier and preparation method and application thereof | 西北工业大学 | 2022-08-23 | — | — | CN | claimed |
| WO-2022012550-A1 | SUBSTITUTED 1H-IMIDAZO [1, 2-B] PYRAZOLE-3-CARBOXAMIDE AS BRUTON'S TYROSINE KINASE INHIBITORS | HENAN NORMAL UNIVERSITY (CN) | 2022-01-20 | — | — | WO | claimed |
| EP-3847220-A1 | UV-CURABLE HOT MELT ADHESIVE COMPOSITIONS FOR FLOORING APPLICATIONS | BASF SE (DE) | 2021-07-14 | — | — | EP | claimed |
| CN-113082220-A | pH-responsive surface charge reversal nano-carrier and preparation method and application thereof | 西北工业大学 | 2021-07-09 | — | — | CN | claimed |
| WO-2021110142-A1 | SUBSTITUTED IMIDAZOLECARBOXAMIDE AS BRUTON'S TYROSINE KINASE INHIBITORS | HENAN NORMAL UNIVERSITY (CN) | 2021-06-10 | — | — | WO | claimed |
| CN-112585230-A | UV curable hot melt adhesive composition for floor application | 巴斯夫欧洲公司 | 2021-03-30 | — | — | CN | claimed |
| EP-2915186-B1 | FORMULATIONS OF SOLUTIONS AND PROCESSES FOR FORMING A SUBSTRATE INCLUDING AN ARSENIC DOPANT | VERSUM MAT US LLC (US) | 2020-10-28 | — | — | EP | claimed |
| CN-110483691-A | A kind of terpolymer crosslinking agent and its application in the dedicated cationic membrane preparation of diffusion dialysis | UNIV ANHUI | 2019-11-22 | — | — | CN | claimed |
| CN-110403915-A | DNA and the hybridized nucleic acids pharmaceutical carrier of polymer and its preparation method and application | UNIV TIANJIN | 2019-11-05 | — | — | CN | claimed |
| CN-110194877-A | A kind of Nanometer composite hydrogel and its preparation method and application | 湘潭大学 | 2019-09-03 | — | — | CN | claimed |
| CN-106699940-A | Preparing method of composite nanoparticle based on polypropylene amide benzene boric acid | 华北科技学院 | 2017-05-24 | — | — | CN | claimed |
| CN-103977776-B | The quick intelligent aqueous gel capable of a kind of sugar based on gold surface and synthetic method thereof | SUZHOU QUANTZ MEDICAL TECHNOLOGY CO., LTD. (CN) | 2016-04-13 | — | — | CN | claimed |
| CN-104148038-B | A kind of based on gold surface boric acid class glucose-sensitive type trace hydrogel and preparation method thereof | SUZHOU QUANTZ MEDICAL TECHNOLOGY CO., LTD. (CN) | 2016-02-10 | — | — | CN | claimed |
| CN-104148038-A | Boric acid glucose-sensitive imprinted hydrogel based on gold surface and preparation method of hydrogel | SUZHOU KANGCI MEDICAL TECHNOLOGY CO LTD | 2014-11-19 | — | — | CN | claimed |
| CN-103977776-A | Sugar-sensitive intelligent hydrogel based on gold surface and synthesis method thereof | SUZHOU QUANTZ MEDICAL TECHNOLOGY CO LTD | 2014-08-13 | — | — | CN | claimed |
| US-20110281821-A9 | Modulators of Mitotic Kinases | BIOGEN IDEC MA INC. (US) | 2011-11-17 | — | — | US | claimed |
| US-20100249067-A1 | Modulators of Mitotic Kinases | BIOGEN IDEC MA INC. (US) | 2010-09-30 | — | — | US | claimed |
| CN-101616920-A | The 1-H-pyrazolo (3,4b) pyrimidine derivatives and as the purposes of mitotic kinase conditioning agent | BIOGEN IDEC INC | 2009-12-30 | — | — | CN | claimed |
| EP-2108020-A2 | 1-H-PYRAZOLO[3,4B]PYRIMIDINE DERIVATIVES AND THEIR USE AS MODULATORS OF MITOTIC KINASES | Biogen Idec MA, Inc. (US) | 2009-10-14 | — | — | EP | claimed |
| WO-2008094602-A2 | 1-H-PYRAZOLO (3,4B) PYRIMIDINE DERIVATIVES AND THEIR USE AS MODULATORS OF MITOTIC KINASES | BIOGEN IDEC MA INC. (US) | 2008-08-07 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249067-A1 | Modulators of Mitotic Kinases | BUB1, BUB1B, CDK1 | TGM2 3581/4885F13A1 4237/4885TGM1 1397/4885 |
| US-20110281821-A9 | Modulators of Mitotic Kinases | BUB1, BUB1B, CDK1 | TGM2 3581/4885F13A1 4237/4885TGM1 1397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.