Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.50 |
| ▸ | CTSS | P25774 | 6/20 | 0.50 |
| ▸ | PPARA | Q07869 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22987316 | 0.84 | MEN1 (0.45) | CTSKCTSSPPARAPPARGCTSL | |
| SCHEMBL1951491 | 0.83 | CTSK (0.64) | CTSKCTSSPPARAPPARGCTSL | |
| SCHEMBL47301 | 0.83 | TGFBR1 (0.52) | CTSKCTSSPPARAPPARGCTSL | |
| SCHEMBL835996 | 0.83 | CTSK (0.64) | CTSKCTSSPPARAPPARGCTSL | |
| SCHEMBL318796 | 0.83 | CTSK (0.64) | CTSKCTSSPPARAPPARGCTSL | |
| SCHEMBL315980 | 0.83 | TGFBR1 (0.52) | CTSKCTSSPPARAPPARGCTSL | |
| SCHEMBL47290 | 0.83 | TGFBR1 (0.52) | CTSKCTSSPPARAPPARGCTSL | |
| SCHEMBL2769978 | 0.82 | FOLH1 (0.56) | CTSKCTSSPPARAPPARGACE | |
| SCHEMBL1318658 | 0.82 | FOLH1 (0.56) | CTSKCTSSPPARAPPARGACE | |
| SCHEMBL1324835 | 0.82 | FOLH1 (0.56) | CTSKCTSSPPARAPPARGACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015095301-A2 | CYTOTOXIC PEPTIDES AND CONJUGATES THEREOF | IRM LLC (BM) | 2015-06-25 | — | — | WO | disclosed |