SCHEMBL47301

SCHEMBL47301

CC(C)(C)OC(=O)N[C@H](CO)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 3/20 0.52
CTSS P25774 6/20 0.51
CTSK P43235 6/20 0.51
PPARA Q07869 6/20 0.49
PPARG P37231 5/20 0.49
CTSL P07711 1/20 0.49
CTSB P07858 1/20 0.49
ACE P12821 1/20 0.48
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
PPARD Q03181 2/20 0.47
MEN1 O00255 1/20 0.46
GAA P10253 1/20 0.46
KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL47290 1.00 TGFBR1 (0.52) TGFBR1CTSSCTSKPPARAPPARG
SCHEMBL315980 1.00 TGFBR1 (0.52) TGFBR1CTSSCTSKPPARAPPARG
Water SCHEMBL23833041 0.98 CTSS (0.54) TGFBR1CTSSCTSKPPARAPPARG
Ammonia Solution, Strong SCHEMBL28315164 0.98 CTSK (0.50) TGFBR1CTSSCTSKPPARAPPARG
Water SCHEMBL31557653 0.98 CTSS (0.54) TGFBR1CTSSCTSKPPARAPPARG
Propene SCHEMBL3265526 0.92 CTSK (0.46) TGFBR1CTSSCTSKPPARAPPARG
SCHEMBL12980339 0.89 CTSK (0.61) TGFBR1CTSSCTSKPPARAPPARG
SCHEMBL12980341 0.89 CTSK (0.61) TGFBR1CTSSCTSKPPARAPPARG
Valine SCHEMBL5916993 0.87 CA1 (0.45) TGFBR1CTSSCTSKPPARAPPARG
SCHEMBL29414393 0.87 CTSS (0.46) TGFBR1CTSSCTSKPPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 595 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120058547-A Method for preparing lacosamide 湖北葛店人福药业有限责任公司 2025-05-30 CN claimed
CN-118812395-A Method for synthesizing lacosamide intermediate 浙江普洛家园药业有限公司 2024-10-22 CN claimed
CN-115198386-B Microporous pure protein fiber and preparation method thereof 邦特云纤(青岛)新材料科技有限公司 2024-02-06 CN claimed
CN-116041441-A Synthesis method of daptomycin 申联生物医药(上海)股份有限公司 2023-05-02 CN claimed
CN-218530097-U BOC-D-serine preparation filter equipment 江苏吉泰肽业科技有限公司 2023-02-28 CN claimed
CN-115198386-A Microporous pure protein fiber and preparation method thereof 邦特云纤(青岛)新材料科技有限公司 2022-10-18 CN claimed
CN-114685317-A Preparation method of medicine for treating epilepsy 成都硕德药业有限公司 2022-07-01 CN claimed
EP-2444390-B1 Process for producing Lacosamide EUTICALS GMBH (DE) 2017-02-01 EP claimed
US-8598386-B2 Process for producing lacosamide EUTICALS GMBH (DE) 2013-12-03 US claimed
CN-101928230-B Improved synthesis scheme for lacosamide UCB PHARMA GMBH 2012-11-07 CN claimed
EP-2444390-A1 Process for producing Lacosamide Archimica GmbH (DE) 2012-04-25 EP claimed
US-20120095251-A1 Process for Producing Lacosamide EUTICALS GMBH (DE) 2012-04-19 US claimed
CN-1989102-B Improved lacosamide synthesis method UCB PHARMA GMBH 2011-04-20 CN claimed
CN-101928230-A The synthetic method of improved scheme for lacosamide UCB PHARMA SA 2010-12-29 CN claimed
US-20260091024-A1 PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE BIOHAVEN THERAPEUTICS LTD (US) 2026-04-02 US disclosed
EP-4426683-B1 BENZODIAZEPINE DERIVATIVES AS POSITIVE ALLOSTERIC MODULATORS OF THE GABA A GAMMA1 RECEPTOR HOFFMANN LA ROCHE (CH) 2026-04-01 EP disclosed
US-20260070912-A1 BENZODIAZEPINE DERIVATIVES AS GABA A GAMMA1 PAM HOFFMANN-LA ROCHE INC. (US) 2026-03-12 US disclosed
US-4338437-A Cephalosporin antibiotics MERCK & CO., INC. (US) 1982-07-06 US disclosed
US-4324890-A ANTIBIOTICS, BACTERICIDES MERCK & CO., INC. (US) 1982-04-13 US disclosed
EP-0022621-A1 Peptides related to somatostatin, their preparation and pharmaceutical compositions containing them ELI LILLY AND COMPANY (US) 1981-01-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091024-A1 PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE IL6ST, GFRA3, GFRA1 TGFBR1 566/4885CTSS 1265/4885CTSK 1499/4885
US-20120095251-A1 Process for Producing Lacosamide NAAA, TET3, GNMT TGFBR1 4226/4885CTSS 2498/4885CTSK 2733/4885
US-20260070912-A1 BENZODIAZEPINE DERIVATIVES AS GABA A GAMMA1 PAM GABRA1, GABRB1, GABRA6 TGFBR1 1500/4885CTSS 4402/4885CTSK 4004/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.