Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.32 |
| ▸ | OGFRL1 | Q5TC84 | 9/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16856774 | 0.85 | NR3C1 (0.33) | — | |
| SCHEMBL16856761 | 0.79 | ALDH1A1 (0.40) | ADORA2AHPGDLMNATSHROPRK1 | |
| SCHEMBL16856751 | 0.73 | ADORA2A (0.34) | ADORA2A | |
| SCHEMBL16856760 | 0.70 | KDM4C (0.38) | TSHROPRM1SMN1; SMN2OPRL1 | |
| SCHEMBL16856745 | 0.68 | P2RY14 (0.33) | TSHR | |
| SCHEMBL16856738 | 0.67 | NOTUM (0.34) | TDP1 | |
| SCHEMBL28863344 | 0.66 | BTK (0.43) | HPGDLMNATSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL16856775 | 0.65 | HCAR2 (0.36) | HPGDLMNATSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL20816394 | 0.64 | HCAR3 (0.39) | ADORA2AHSD17B10HCAR3GAAALDH1A1 | |
| SCHEMBL16856753 | 0.63 | SCD (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2889292-B1 | 2-SUBSTITUTED-2H-1, 2, 3-TRIAZOLE DERIVATIVE AND PREPARATION METHOD THEREOF | ABA CHEMICALS CORP (CN) | 2020-03-25 | — | — | EP | disclosed |
| US-9586912-B2 | 2-substituted-2H-1, 2, 3-triazole derivative and its preparation method | ABA CHEMICALS CORPORATION (CN) | 2017-03-07 | — | — | US | disclosed |
| US-9586912-B2 | 2-substituted-2H-1, 2, 3-triazole derivative and its preparation method | ABA CHEMICALS CORPORATION (CN) | 2017-03-07 | — | — | US | disclosed |
| US-9586912-B2 | 2-substituted-2H-1, 2, 3-triazole derivative and its preparation method | ABA CHEMICALS CORPORATION (CN) | 2017-03-07 | — | — | US | disclosed |
| US-20150232431-A1 | 2-SUBSTITUTED-2H-1, 2, 3-TRIAZOLE DERIVATIVE AND ITS PREPARATION METHOD | ABA CHEMICALS CORPORATION (CN) | 2015-08-20 | — | — | US | disclosed |
| US-20150232431-A1 | 2-SUBSTITUTED-2H-1, 2, 3-TRIAZOLE DERIVATIVE AND ITS PREPARATION METHOD | ABA CHEMICALS CORPORATION (CN) | 2015-08-20 | — | — | US | disclosed |
| US-20150232431-A1 | 2-SUBSTITUTED-2H-1, 2, 3-TRIAZOLE DERIVATIVE AND ITS PREPARATION METHOD | ABA CHEMICALS CORPORATION (CN) | 2015-08-20 | — | — | US | disclosed |
| EP-2889292-A1 | 2-SUBSTITUTED-2H-1, 2, 3-TRIAZOLE DERIVATIVE AND PREPARATION METHOD THEREOF | ABA Chemicals Corporation (CN) | 2015-07-01 | — | — | EP | disclosed |
| EP-2889292-A1 | 2-SUBSTITUTED-2H-1, 2, 3-TRIAZOLE DERIVATIVE AND PREPARATION METHOD THEREOF | ABA Chemicals Corporation (CN) | 2015-07-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150232431-A1 | 2-SUBSTITUTED-2H-1, 2, 3-TRIAZOLE DERIVATIVE AND ITS PREPARATION METHOD | CYP1A2, CYP1B1, CYP3A5 | ADORA2A 1169/4885HPGD 1048/4885LMNA 4095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.