Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16856761 | 0.95 | ALDH1A1 (0.40) | NPSR1ALDH1A1HSD17B10CNR2SMN1; SMN2 | |
| SCHEMBL16856739 | 0.94 | NPSR1 (0.39) | NPSR1ALDH1A1HSD17B10CNR2ATM | |
| SCHEMBL16856730 | 0.77 | ADORA2A (0.34) | ALDH1A1HSD17B10SMN1; SMN2HPGDLMNA | |
| SCHEMBL26664816 | 0.67 | OPRK1 (0.36) | NPSR1ALDH1A1HSD17B10CNR2SMN1; SMN2 | |
| SCHEMBL16856774 | 0.67 | NR3C1 (0.33) | CNR2 | |
| SCHEMBL16856751 | 0.65 | ADORA2A (0.34) | ADORA2A | |
| SCHEMBL2077051 | 0.64 | ELANE (0.54) | ALDH1A1HSD17B10SMN1; SMN2TSHRKDM4E | |
| SCHEMBL9091123 | 0.63 | NPSR1 (0.71) | NPSR1ALDH1A1HSD17B10SMN1; SMN2L3MBTL1 | |
| SCHEMBL20495112 | 0.61 | NPSR1 (0.40) | NPSR1ALDH1A1HSD17B10SMN1; SMN2L3MBTL1 | |
| SCHEMBL29878378 | 0.61 | NPSR1 (0.48) | NPSR1ALDH1A1HSD17B10SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2889292-B1 | 2-SUBSTITUTED-2H-1, 2, 3-TRIAZOLE DERIVATIVE AND PREPARATION METHOD THEREOF | ABA CHEMICALS CORP (CN) | 2020-03-25 | — | — | EP | disclosed |
| US-9586912-B2 | 2-substituted-2H-1, 2, 3-triazole derivative and its preparation method | ABA CHEMICALS CORPORATION (CN) | 2017-03-07 | — | — | US | disclosed |
| US-20150232431-A1 | 2-SUBSTITUTED-2H-1, 2, 3-TRIAZOLE DERIVATIVE AND ITS PREPARATION METHOD | ABA CHEMICALS CORPORATION (CN) | 2015-08-20 | — | — | US | disclosed |
| EP-2889292-A1 | 2-SUBSTITUTED-2H-1, 2, 3-TRIAZOLE DERIVATIVE AND PREPARATION METHOD THEREOF | ABA Chemicals Corporation (CN) | 2015-07-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150232431-A1 | 2-SUBSTITUTED-2H-1, 2, 3-TRIAZOLE DERIVATIVE AND ITS PREPARATION METHOD | CYP1A2, CYP1B1, CYP3A5 | NPSR1 2299/4885ALDH1A1 104/4885HSD17B10 707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.