SCHEMBL168576

SCHEMBL168576

[CH2]CCC(C(=O)O)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPEP Q07075 1/20 0.40
TDP1 Q9NUW8 2/20 0.35
CHRM1 P11229 1/20 0.35
AKR1A1 P14550 1/20 0.35
CHRM3 P20309 1/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
ADRA1A P35348 1/20 0.35
HRH1 P35367 1/20 0.35
DRD3 P35462 1/20 0.35
SLC6A3 Q01959 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35
PTGS1 P23219 1/20 0.35
SLC7A11 Q9UPY5 1/20 0.35
TET2 Q6N021 3/20 0.33
KDM4A O75164 2/20 0.33
KDM4C Q9H3R0 2/20 0.33
KDM2A Q9Y2K7 2/20 0.33
FOLH1 Q04609 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29009716 0.97 ENPEP (0.39) ENPEPTDP1CHRM1AKR1A1CHRM3
SCHEMBL4622721 0.83 CHRM1 (0.35) ENPEPTDP1CHRM1AKR1A1CHRM3
SCHEMBL165787 0.81 ENPEP (0.37) ENPEPTDP1CHRM1AKR1A1CHRM3
SCHEMBL167930 0.79 TBXAS1 (0.36) ENPEPFOLH1CYP1A2GSRTSHR
SCHEMBL28123 0.78 ENPEP (0.55) ENPEPTDP1CHRM1AKR1A1CHRM3
SCHEMBL168927 0.77 TBXAS1 (0.39) ENPEPFOLH1GSRGRIK1GRIK2
SCHEMBL168355 0.77 TBXAS1 (0.39) ENPEPFOLH1GSRGRIK1GRIK2
SCHEMBL165661 0.77 TBXAS1 (0.39) ENPEPFOLH1GSRGRIK1GRIK2
SCHEMBL27856541 0.77 TBXAS1 (0.39) ENPEPFOLH1GSRGRIK1GRIK2
SCHEMBL27574099 0.77 TBXAS1 (0.39) ENPEPFOLH1GSRGRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4381345-A1 SWITCHING LAYERS FOR USE IN A WINDOW ELEMENT Merck Patent GmbH (DE) 2024-06-12 EP disclosed
EP-3704176-B1 ORGANIC SEMICONDUCTING COMPOUNDS RAYNERGY TEK INC (TW) 2024-05-15 EP disclosed
US-20240134218-A1 DEVICE FOR THE REGULATION OF LIGHT TRANSMISSION MERCK PATENT GMBH (DE) 2024-04-25 US disclosed
US-11958819-B2 Compounds for optically active devices Johnson & Johnson Surgical Vision, Inc. (US) 2024-04-16 US disclosed
US-11952528-B2 Switching layers for use in a switching element MERCK PATENT GMBH (DE) 2024-04-09 US disclosed
CN-117795407-A Switching layer for window element 默克专利股份有限公司 2024-03-29 CN disclosed
CN-111433323-B Liquid-crystalline medium for switching elements 默克专利股份有限公司 2024-03-22 CN disclosed
CN-113544186-B Organic semiconductor composition 天光材料科技股份有限公司 2024-03-19 CN disclosed
EP-3794650-B1 ORGANIC SEMICONDUCTORS RAYNERGY TEK INC (TW) 2024-03-13 EP disclosed
CN-107915661-B Organic semiconductor compound 天光材料科技股份有限公司 2024-01-23 CN disclosed
WO-1990012073-A1 TRIFLUOROMETHYLCYCLOHEXANE DERIVATIVES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-10-18 WO disclosed
EP-0381728-A1 DIFLUOROMETHYL COMPOUNDS. MERCK PATENT GMBH (DE) 1990-08-16 EP disclosed
EP-0367771-A1 ARYL SULPHUR PENTAFLUORIDES. MERCK PATENT GMBH (DE) 1990-05-16 EP disclosed
US-4925590-A Derivatives of 4-cyano-2,3-difluorophenol MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1990-05-15 US disclosed
WO-1990001056-A1 DIFLUOROMETHYL COMPOUNDS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-02-08 WO disclosed
EP-0329752-A1 FLUORINATED OLIGOPHENYLS AND THEIR USE IN LIQUID CRYSTAL MATERIALS MERCK PATENT GmbH (DE) 1989-08-30 EP disclosed
WO-1989002425-A1 FLUORINATED OLIGOPHENYLS AND THEIR USE IN LIQUID CRYSTAL MATERIALS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1989-03-23 WO disclosed
WO-1988010251-A1 ARYL SULPHUR PENTAFLUORIDES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1988-12-29 WO disclosed
EP-0159913-B1 SILVER HALIDE PHOTOGRAPHIC LIGHT SENSITIVE MATERIAL KONICA CORPORATION (JP) 1988-09-14 EP disclosed
EP-0159913-A1 Silver halide photographic light sensitive material KONICA CORPORATION (JP) 1985-10-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11958819-B2 Compounds for optically active devices PDE6C, ALDH1A2, PDE6A ENPEP 844/4885TDP1 1350/4885CHRM1 2209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.