SCHEMBL165787

SCHEMBL165787

[CH2]CCCC(C(=O)O)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPEP Q07075 1/20 0.37
TBXAS1 P24557 1/20 0.33
CYP1A2 P05177 1/20 0.32
GLA P06280 1/20 0.32
TSHR P16473 1/20 0.32
NFKB1 P19838 1/20 0.32
APEX1 P27695 1/20 0.32
CYP2C19 P33261 1/20 0.32
NOS2 P35228 1/20 0.32
GSR P00390 1/20 0.32
CA2 P00918 1/20 0.32
MAPK1 P28482 1/20 0.32
CHRM1 P11229 1/20 0.32
AKR1A1 P14550 1/20 0.32
CHRM3 P20309 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
ADRA1A P35348 1/20 0.32
HRH1 P35367 1/20 0.32
DRD3 P35462 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL167930 0.92 TBXAS1 (0.36) ENPEPTBXAS1CYP1A2GLATSHR
SCHEMBL27574099 0.89 TBXAS1 (0.39) ENPEPTBXAS1GSRGPR84RNPEP
SCHEMBL168046 0.89 TBXAS1 (0.39) ENPEPTBXAS1GSRGPR84RNPEP
SCHEMBL168355 0.89 TBXAS1 (0.39) ENPEPTBXAS1GSRGPR84RNPEP
SCHEMBL168927 0.89 TBXAS1 (0.39) ENPEPTBXAS1GSRGPR84RNPEP
SCHEMBL27856541 0.89 TBXAS1 (0.39) ENPEPTBXAS1GSRGPR84RNPEP
SCHEMBL165661 0.89 TBXAS1 (0.39) ENPEPTBXAS1GSRGPR84RNPEP
SCHEMBL4621122 0.85 CA2 (0.32) CYP1A2CYP2C19NOS2CA2MAPK1
SCHEMBL29068324 0.84 TBXAS1 (0.31) TBXAS1
SCHEMBL168576 0.81 ENPEP (0.40) ENPEPCYP1A2TSHRGSRCHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1066 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4381345-A1 SWITCHING LAYERS FOR USE IN A WINDOW ELEMENT Merck Patent GmbH (DE) 2024-06-12 EP disclosed
EP-3704176-B1 ORGANIC SEMICONDUCTING COMPOUNDS RAYNERGY TEK INC (TW) 2024-05-15 EP disclosed
US-20240134218-A1 DEVICE FOR THE REGULATION OF LIGHT TRANSMISSION MERCK PATENT GMBH (DE) 2024-04-25 US disclosed
US-11958819-B2 Compounds for optically active devices Johnson & Johnson Surgical Vision, Inc. (US) 2024-04-16 US disclosed
US-11952528-B2 Switching layers for use in a switching element MERCK PATENT GMBH (DE) 2024-04-09 US disclosed
CN-117795407-A Switching layer for window element 默克专利股份有限公司 2024-03-29 CN disclosed
CN-111433323-B Liquid-crystalline medium for switching elements 默克专利股份有限公司 2024-03-22 CN disclosed
CN-113544186-B Organic semiconductor composition 天光材料科技股份有限公司 2024-03-19 CN disclosed
EP-3794650-B1 ORGANIC SEMICONDUCTORS RAYNERGY TEK INC (TW) 2024-03-13 EP disclosed
CN-112424966-B organic semiconductor 天光材料科技股份有限公司 2023-12-26 CN disclosed
WO-1991011418-A1 PARTIALLY FLUORINATED COMPOUNDS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1991-08-08 WO disclosed
WO-1991008184-A2 1,2-DISUBSTITUTED 2,6-DIFLUOROBENZENE COMPOUNDS AND LIQUID CRYSTAL MEDIA MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1991-06-13 WO disclosed
EP-0418362-A1 TRIFLUOROMETHYLCYCLOHEXANE DERIVATIVES. MERCK PATENT GMBH (DE) 1991-03-27 EP disclosed
WO-1990012073-A1 TRIFLUOROMETHYLCYCLOHEXANE DERIVATIVES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-10-18 WO disclosed
EP-0381728-A1 DIFLUOROMETHYL COMPOUNDS. MERCK PATENT GMBH (DE) 1990-08-16 EP disclosed
EP-0367771-A1 ARYL SULPHUR PENTAFLUORIDES. MERCK PATENT GMBH (DE) 1990-05-16 EP disclosed
US-4925590-A Derivatives of 4-cyano-2,3-difluorophenol MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1990-05-15 US disclosed
WO-1990001056-A1 DIFLUOROMETHYL COMPOUNDS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-02-08 WO disclosed
WO-1989002425-A1 FLUORINATED OLIGOPHENYLS AND THEIR USE IN LIQUID CRYSTAL MATERIALS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1989-03-23 WO disclosed
WO-1988010251-A1 ARYL SULPHUR PENTAFLUORIDES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1988-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11958819-B2 Compounds for optically active devices PDE6C, ALDH1A2, PDE6A ENPEP 844/4885TBXAS1 678/4885CYP1A2 1448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.