MMP15 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL3534852	0.77	11/20
SCHEMBL3534115	0.67	11/20
SCHEMBL3534006	0.66	11/20
SCHEMBL3537910	0.63	11/20
SCHEMBL1021988	0.63	11/20
SCHEMBL5439966	0.60	11/20
SCHEMBL5439969	0.60	11/20
SCHEMBL1022551	0.58	11/20
SCHEMBL1022069	0.57	11/20
SCHEMBL1023240	0.56	11/20
SCHEMBL5445428	0.56	11/20
SCHEMBL1022410	0.54	11/20
SCHEMBL5164250	0.69	10/20
SCHEMBL3536039	0.67	10/20
SCHEMBL4692975	0.56	10/20
SCHEMBL5451005	0.56	10/20
SCHEMBL5431767	0.51	10/20
SCHEMBL5431771	0.51	10/20
SCHEMBL5449195	0.51	10/20
SCHEMBL1020024	0.66	9/20

Clinical trials — most relevant to MMP15 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Estimation of MMP-8 Levels in GCF and Serum and Its Correlation With Wound Healing and Clinical Outcomes After Coronally Advanced Flap and Subepithelial Connective Tissue Graft for Root Coverage in Recession Defects: A CLINICO-BIOCHEMICAL STUDY	PHASE4	SUSPENDED
Doxycycline In Lymphangioleiomyomatosis (LAM)	PHASE4	COMPLETED
Sputum Matrix Metalloproteinases (MMP) mRNA and Montelukast	PHASE2	COMPLETED
The Role of Matrix Metalloproteinases (MMPs) in Orthodontic Tooth Movement	PHASE1	COMPLETED
A Phase I Study of Oral COL-3 (NSC-683551), a Matrix Metalloproteinase Inhibitor, in Patients With Refractory Metastatic Cancer	PHASE1	COMPLETED
Re-evaluation of Some Old Rheumatoid Arthritis Therapy: A Randomized Controlled Trial	nan	COMPLETED
Influence of Statins in Artery Aneurysms	nan	UNKNOWN
Evaluation of Different Serum Cartilage Biomarkers in the Acute Response to Walking and Cycling in Healthy Male Subjects	nan	AVAILABLE
Role of A Disintegrin and Metalloproteinase (ADAM) in Epithelial Dysfunction	nan	COMPLETED
Influence of Short AV Delay Permanent Pacing on Matrix Metalloproteinase Levels	nan	COMPLETED
Periodontal Health in Post COVID-19 Patients	nan	UNKNOWN
Case-control Study on Matrix Metalloproteinase Levels in Tissue in Patients With Keloid Scar	nan	COMPLETED
Plasma Levels of Matrix Metalloproteinases (MMPs) and Degree of DNA Fragmentation in Pseudoexfoliation (PEX) Glaucoma	nan	COMPLETED
Plasma and Scarring of Diabetic Ulcers	nan	COMPLETED
Association Between Matrix Metalloproteinase-2 Gene Polymorphism rs243865 and Susceptibility to Cataract Development	nan	COMPLETED
Detection of Cancer-Specific Active Proteases in Blood Via Fluorescence	nan	WITHDRAWN
Apoptotic Changes in Gingiva Caused by Smoking	nan	COMPLETED
The Effect of Non-surgical Periodontal Therapy Plus Doxycycline on HbA1c in Patients With Type 2 Diabetes Mellitus	nan	COMPLETED
Salivary Markers in Periodontal Disorders	nan	COMPLETED
miRNA-452 in Patients With Preeclampsia and Its Correlation With MMP-9	nan	COMPLETED
The Impact of Pregnancy and Pregnancy-associated Hypertension on Human Uterine Myometrial Artery Reactivity	nan	WITHDRAWN
Role of Extracellular Matrix in the Development of Airway Remodeling in Asthma	nan	UNKNOWN
Correlation Between Serum Markers of Unstable Plaque and Virtual Histology of Unstable Plaque Visualized by IVUS	nan	COMPLETED
Matrix Metalloproteinases 7 and 9 in Rheumatoid Arthritis Patients With Interstitial Lung Disease	nan	NOT_YET_RECRUITING
Matrix Metalloproteinase (MMP) in Heart Failure	nan	COMPLETED
Cancer Fusion Hybrids and Desmoplasia	nan	UNKNOWN
Serum COMP and MMP-3 in Knee Osteoarthritis	nan	NOT_YET_RECRUITING
Matrix Metalloproteinases and Human Papillomavirus in Dysplasias and Cancers of the Cervix	nan	COMPLETED
Evaluation of Dentinal Fluid for the Presence of Matrix Metalloproteinase 9 (MMP-9) in Pulpal Inflammation	nan	COMPLETED
Extracellular Matrix Marker of Arrhythmia Risk (EMMA)	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a MMP15 binder may also engage these)

Protein	Name	Similarity
O54732	—	1.000	O54732 →
MMP24	Matrix metalloproteinase-24	1.000	landscape →
Q95220	—	1.000	Q95220 →
MMP14	Matrix metalloproteinase-14	0.999	landscape →
Q10739	—	0.998	Q10739 →
P53690	—	0.998	P53690 →
Q3U435	—	0.997	Q3U435 →
Q5RES1	—	0.996	Q5RES1 →
Q9GLE4	—	0.996	Q9GLE4 →
P41245	—	0.993	P41245 →
Q9R0S2	—	0.993	Q9R0S2 →
P52176	—	0.993	P52176 →
Q99PW6	—	0.992	Q99PW6 →
Q9WTR0	—	0.992	Q9WTR0 →
Q9XT90	—	0.992	Q9XT90 →
MMP9	Matrix metalloproteinase-9	0.991	landscape →
Q08E66	—	0.990	Q08E66 →
Q8TEU8	—	0.990	Q8TEU8 →
P41246	—	0.989	P41246 →
Q8IXK2	—	0.989	Q8IXK2 →
Q499S5	—	0.989	Q499S5 →
B4F6N6	—	0.988	B4F6N6 →
O88917	—	0.988	O88917 →
O35548	—	0.988	O35548 →
P50757	—	0.987	P50757 →
LOXL3	Lysyl oxidase homolog 3	0.987	landscape →
P57748	—	0.987	P57748 →
Q9R097	—	0.987	Q9R097 →
Q9GLE5	—	0.987	Q9GLE5 →
Q8MPP3	—	0.987	Q8MPP3 →