Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.42 |
| ▸ | UGT2B17 | O75795 | 2/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5993417 | 0.94 | UHRF1 (0.47) | UHRF1UGT2B17NUDT1ALDH1A1GAA | |
| SCHEMBL1761215 | 0.88 | UGT2B17 (0.36) | UHRF1UGT2B17NUDT1ALDH1A1GAA | |
| SCHEMBL22312385 | 0.77 | UHRF1 (0.40) | UHRF1NUDT1ALDH1A1GAAHSD17B10 | |
| SCHEMBL1686017 | 0.77 | UHRF1 (0.40) | UHRF1NUDT1ALDH1A1GAAHSD17B10 | |
| SCHEMBL22435470 | 0.74 | ALDH1A1 (0.38) | UHRF1NUDT1ALDH1A1GAAHSD17B10 | |
| SCHEMBL24297724 | 0.73 | NUDT1 (0.43) | UHRF1NUDT1ALDH1A1ATMNOS3 | |
| SCHEMBL31170775 | 0.72 | PARP1 (0.44) | UHRF1NUDT1ALDH1A1MAPTHTR1D | |
| SCHEMBL6221804 | 0.72 | PARP1 (0.44) | UHRF1NUDT1ALDH1A1MAPTHTR1D | |
| SCHEMBL5467021 | 0.71 | MAPT (0.49) | ALDH1A1GAAHSD17B10MAPTATM | |
| SCHEMBL20939380 | 0.69 | NOTUM (0.42) | UHRF1NUDT1ALDH1A1GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169773-B2 | Compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2007-01-30 | — | — | US | disclosed |
| US-20070010537-A1 | Fused pyramidine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-11 | — | — | US | disclosed |
| US-20070010537-A1 | Fused pyramidine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-11 | — | — | US | disclosed |
| US-20070010537-A1 | Fused pyramidine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-11 | — | — | US | disclosed |
| EP-1657238-A1 | FUSED PYRIMIDINE DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2006-05-17 | — | — | EP | disclosed |
| US-20060003991-A1 | Compounds | SZEWCZYK JERZY R | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010537-A1 | Fused pyramidine derivative and use thereof | NR5A1, GNRHR, RXFP3 | UHRF1 2935/4885UGT2B17 1631/4885NUDT1 504/4885 |
| US-20060003991-A1 | Compounds | SLC10A1, SLC10A2, ABCB11 | UHRF1 4553/4885UGT2B17 26/4885NUDT1 2694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.