Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16859411 | 0.84 | SMN1; SMN2 (0.37) | SMN1; SMN2CA14CA12CA9CA7 | |
| SCHEMBL16859410 | 0.84 | SMN1; SMN2 (0.37) | SMN1; SMN2CA14CA12CA9CA7 | |
| SCHEMBL17423668 | 0.84 | SMN1; SMN2 (0.37) | SMN1; SMN2CA14CA12CA9CA7 | |
| SCHEMBL21052301 | 0.84 | SMN1; SMN2 (0.41) | SMN1; SMN2CA14CA12CA9CA7 | |
| SCHEMBL18124656 | 0.82 | CA1 (0.45) | SMN1; SMN2CA14CA12CA9CA7 | |
| SCHEMBL28977201 | 0.82 | CA1 (0.34) | CA12CA9CA1CA2 | |
| SCHEMBL18124693 | 0.82 | CA1 (0.45) | SMN1; SMN2CA14CA12CA9CA7 | |
| SCHEMBL18124651 | 0.82 | CA1 (0.45) | SMN1; SMN2CA14CA12CA9CA7 | |
| SCHEMBL7990686 | 0.82 | SMN1; SMN2 (0.43) | SMN1; SMN2CA14CA12CA9CA7 | |
| SCHEMBL8161959 | 0.80 | ALDH1A1 (0.39) | SMN1; SMN2CA12CA9CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9974304-B2 | Use of macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2018-05-22 | — | — | US | disclosed |
| US-20180037541-A1 | PICOLINAMIDES WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC | 2018-02-08 | — | — | US | disclosed |
| US-20170369421-A1 | PICOLINAMIDES WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC | 2017-12-28 | — | — | US | disclosed |
| US-20170273303-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | CORTEVA AGRISCIENCE LLC | 2017-09-28 | — | — | US | disclosed |
| US-9686984-B2 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2017-06-27 | — | — | US | disclosed |
| US-9549555-B2 | Macrocyclic picolinamide compounds with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2017-01-24 | — | — | US | disclosed |
| US-9549556-B2 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2017-01-24 | — | — | US | disclosed |
| US-9247741-B2 | Use of macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2016-02-02 | — | — | US | disclosed |
| US-20160007602-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2016-01-14 | — | — | US | disclosed |
| US-20150181867-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2015-07-02 | — | — | US | disclosed |
| US-20150183759-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC | 2015-07-02 | — | — | US | disclosed |
| US-20150181868-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2015-07-02 | — | — | US | disclosed |
| US-20150181869-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2015-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150181868-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | FKBP14, CYP4F12, CYP1A2 | SMN1; SMN2 2481/4885CA14 1966/4885CA12 1327/4885 |
| US-20180037541-A1 | PICOLINAMIDES WITH FUNGICIDAL ACTIVITY | CYP51A1, CYP1A2, FKBP14 | SMN1; SMN2 2904/4885CA14 2654/4885CA12 2056/4885 |
| US-20170273303-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | CYP4F12, CYP1A2, FKBP2 | SMN1; SMN2 1902/4885CA14 1340/4885CA12 801/4885 |
| US-20150183759-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | CYP51A1, PFAS, AADAC | SMN1; SMN2 2571/4885CA14 3399/4885CA12 3005/4885 |
| US-20150181867-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | FKBP14, CYP4F12, CYP1A2 | SMN1; SMN2 2481/4885CA14 1966/4885CA12 1327/4885 |
| US-20160007602-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | CYP4F12, CYP1A2, FKBP2 | SMN1; SMN2 1902/4885CA14 1340/4885CA12 801/4885 |
| US-20170369421-A1 | PICOLINAMIDES WITH FUNGICIDAL ACTIVITY | CYP51A1, CYP1A2, FKBP14 | SMN1; SMN2 2904/4885CA14 2654/4885CA12 2056/4885 |
| US-20150181869-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | FKBP14, FKBP2, CYP51A1 | SMN1; SMN2 3211/4885CA14 1814/4885CA12 1286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.