SCHEMBL16865440

SCHEMBL16865440

CN1C(=O)N(c2ccccc2)C(=O)C(Cc2ccccc2)(OC(=O)c2ccccc2)C1=O

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.46
KMT2A Q03164 4/20 0.38
TDP1 Q9NUW8 2/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A3 Q01959 1/20 0.38
CASP3 P42574 2/20 0.37
ALDH1A1 P00352 3/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MAPT P10636 1/20 0.35
PKM P14618 1/20 0.35
ENPP2 Q13822 1/20 0.34
ATM Q13315 2/20 0.34
MEN1 O00255 1/20 0.34
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16865402 0.88 ELANE (0.48) ELANEKMT2AALDH1A1MAPTPKM
SCHEMBL16865437 0.77 ALDH1A1 (0.53) ELANEKMT2AALDH1A1MAPTPKM
SCHEMBL16867610 0.74 ELANE (0.46) ELANEKMT2ATDP1ALDH1A1SMN1; SMN2
SCHEMBL16865451 0.74 ELANE (0.51) ELANEALDH1A1
SCHEMBL16865401 0.69 ELANE (0.40) ELANEALDH1A1SMN1; SMN2GAA
SCHEMBL16865418 0.69 ELANE (0.51) ELANEALDH1A1
SCHEMBL16867611 0.69 ELANE (0.51) ELANEALDH1A1
SCHEMBL13879387 0.68 ELANE (0.59) ELANEKMT2AALDH1A1SMN1; SMN2MEN1
SCHEMBL16865394 0.68 ELANE (0.41) ELANEKMT2AALDH1A1SMN1; SMN2MAPT
SCHEMBL16865420 0.68 ELANE (0.54) ELANEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND C1R, C1S, C3AR1 ELANE 2715/4885KMT2A 1571/4885TDP1 3836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.