Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.38 |
| ▸ | HRH2 | P25021 | 4/20 | 0.37 |
| ▸ | HRH1 | P35367 | 4/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19313619 | 0.95 | ALDH1A1 (0.37) | ALDH1A1HDAC1HDAC2KDM4EHPGD | |
| SCHEMBL16841044 | 0.70 | HDAC1 (0.67) | ALDH1A1HDAC1HDAC2KDM4EHPGD | |
| SCHEMBL29444063 | 0.70 | HDAC1 (0.67) | ALDH1A1HDAC1HDAC2KDM4EHPGD | |
| SCHEMBL18079151 | 0.70 | HDAC1 (0.67) | ALDH1A1HDAC1HDAC2KDM4EHPGD | |
| SCHEMBL20275451 | 0.70 | HDAC1 (0.51) | ALDH1A1HDAC1HDAC2KDM4EHPGD | |
| SCHEMBL10894272 | 0.69 | KDM4E (0.56) | ALDH1A1HDAC1HDAC2KDM4EHPGD | |
| SCHEMBL10895077 | 0.69 | KDM4E (0.56) | ALDH1A1HDAC1HDAC2KDM4EHPGD | |
| SCHEMBL14480433 | 0.69 | KDM4E (0.53) | ALDH1A1HDAC1HDAC2KDM4EHPGD | |
| SCHEMBL26602050 | 0.68 | MMP3 (0.66) | ALDH1A1HDAC1HDAC2KDM4EHPGD | |
| SCHEMBL16941068 | 0.68 | CYP11B2 (0.47) | HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758727-B2 | Bimesogenic compounds and mesogenic media | MERCK PATENT GMBH (DE) | 2017-09-12 | — | — | US | disclosed |
| US-9758727-B2 | Bimesogenic compounds and mesogenic media | MERCK PATENT GMBH (DE) | 2017-09-12 | — | — | US | disclosed |
| EP-3087157-B1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2017-09-06 | — | — | EP | disclosed |
| US-20170002268-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2017-01-05 | — | — | US | disclosed |
| US-20170002268-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2017-01-05 | — | — | US | disclosed |
| WO-2015096879-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2015-07-02 | — | — | WO | disclosed |