SCHEMBL2778029

SCHEMBL2778029

Nc1ccc(Nc2ccc(Cl)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.61
CYP1A2 P05177 2/20 0.61
CYP3A4 P08684 2/20 0.61
CYP2C19 P33261 2/20 0.61
ALDH1A1 P00352 1/20 0.61
CYP2C9 P11712 1/20 0.61
ALOX12 P18054 1/20 0.61
HTT P42858 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
RAD52 P43351 1/20 0.56
MAOA P21397 1/20 0.52
MAOB P27338 1/20 0.52
NR4A1 P22736 1/20 0.52
VCP P55072 1/20 0.51
SCN9A Q15858 3/20 0.50
KCNH2 Q12809 1/20 0.49
SCN5A Q14524 1/20 0.49
PRMT1 Q99873 2/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29479572 0.86 MAPT (0.78) MAPTCYP1A2CYP3A4CYP2C19ALDH1A1
SCHEMBL18289620 0.86 MAPT (0.78) MAPTCYP1A2CYP3A4CYP2C19ALDH1A1
SCHEMBL5438258 0.86 MAPT (0.78) MAPTCYP1A2CYP3A4CYP2C19ALDH1A1
SCHEMBL33864 0.86 MAPT (0.78) MAPTCYP1A2CYP3A4CYP2C19ALDH1A1
SCHEMBL12747008 0.86 MAPT (0.78) MAPTCYP1A2CYP3A4CYP2C19ALDH1A1
SCHEMBL5428343 0.86 MAPT (0.78) MAPTCYP1A2CYP3A4CYP2C19ALDH1A1
SCHEMBL1686571 0.86 LMNA (0.57) MAPTCYP1A2CYP3A4CYP2C19ALDH1A1
SCHEMBL9516529 0.86 LMNA (0.57) MAPTCYP1A2CYP3A4CYP2C19ALDH1A1
SCHEMBL8440919 0.83 MAPT (0.74) MAPTCYP1A2CYP3A4CYP2C19ALDH1A1
SCHEMBL1459001 0.83 MAPT (0.74) MAPTCYP1A2CYP3A4CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4154614-A ACRYLONITRILE-HYDROLYSED POLYVINYL ACETATE GRAFT POLYMER NIPPON PAINT CO., LTD. (JP) 1979-05-15 US claimed
CN-115443436-A Laminated film for pattern formation, non-photosensitive screen printing plate, and method for producing same 株式会社村上 2022-12-06 CN disclosed
US-20150197513-A1 ARYL- AND HETEROARYL-SUBSTITUTED BENZENE DERIVATIVES AS MODULATORS OF PI3-KINASE SIGNALLING PATHWAYS NEUROPORE THERAPIES, INC. 2015-07-16 US disclosed
US-7767381-B2 Photosensitive resin composition, and photosensitive film and stencil for screen printing using the photosensitive composition MURAKAMI CO., LTD. (JP) 2010-08-03 US disclosed
CN-100482715-C Anti-bacterial high molecule and its preparation method, anti-bacterial high-molecule covering film and its preparation method and product with said surface covering film ULVAC INC (JP) 2009-04-29 CN disclosed
US-20090099275-A1 Photosensitive Resin Composition, and Photosensitive Film and Stencil for Screen Printing Using the Photosensitive Composition MURAKAMI CO., LTD. (JP) 2009-04-16 US disclosed
US-7279543-B2 Anti-bacterial polymer and method for the preparation thereof, anti-bacterial polymer film and method for the preparation thereof, and article having such a film on the surface thereof ULVAC, INC. (JP) 2007-10-09 US disclosed
CN-1495218-A Anti-bacterial high molecule and its preparation method, anti-bacterial high-molecule covering film and its preparation method and product with said surface covering film ���׿ƹɷ����޹�˾ 2004-05-12 CN disclosed
US-20040077819-A1 Anti-bacterial polymer and method for the preparation thereof, anti-bacterial polymer film and method for the preparation thereof, and article having such a film on the surface thereof ULVAC, INC. (JP) 2004-04-22 US disclosed
EP-1396514-A1 Anti-bacterial polymer and method for the preparation thereof, anti-bacterial polymer film and method for the preparation thereof, and article having such a film on the surface thereof ULVAC, INC. (JP) 2004-03-10 EP disclosed
US-5645975-A QUATERNARY AMMONIUM POLYMERS THE CHROMALINE CORPORATION (US) 1997-07-08 US disclosed
US-5506089-A CONTAINING HETEROCYCLIC QUATERNARY PENDANT GROUP THE CHROMALINE CORPORATION (US) 1996-04-09 US disclosed
WO-1995012148-A1 SCREEN PRINTING STENCIL COMPOSITION WITH IMPROVED WATER RESISTANCE THE CHROMALINE CORPORATION (US) 1995-05-04 WO disclosed
EP-0130804-B1 PHOTOSENSITIVE RESIN COMPOSITION KOGYO GIJUTSUIN (JP) 1989-02-08 EP disclosed
US-4564580-A SAPONIFIED VINYL ACETATE POLYMER REACTED WITH STRYLPYRIDINIUM OR S KOGYO GIJUTSUIN (JP) 1986-01-14 US disclosed
EP-0130804-A2 Photosensitive resin composition KOGYO GIJUTSUIN (JP) 1985-01-09 EP disclosed
US-4232105-A PHENOL-MODIFIED DIAZO RESIN-WATER SOLUBLE ACRYLIC POLYMER LAYER; AMINO RESIN-POLYAMIDE-PIGMENT LAYER; DURABILITY OJI PAPER CO., LTD. (JP) 1980-11-04 US disclosed
US-4163015-A ANTIBACTERIAL AGENTS STERLING DRUG INC. (US) 1979-07-31 US disclosed
US-4154614-A ACRYLONITRILE-HYDROLYSED POLYVINYL ACETATE GRAFT POLYMER NIPPON PAINT CO., LTD. (JP) 1979-05-15 US disclosed
US-4138405-A BACTERICIDES STERLING DRUG INC. (US) 1979-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150197513-A1 ARYL- AND HETEROARYL-SUBSTITUTED BENZENE DERIVATIVES AS MODULATORS OF PI3-KINASE SIGNALLING PATHWAYS TFEB, ULK1, MTOR MAPT 2673/4885CYP1A2 2366/4885CYP3A4 2288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.