SCHEMBL16867115

SCHEMBL16867115

O=CN(C=O)c1nc(-c2ccccc2)nc(N(CO)CO)n1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
ACP1 P24666 2/20 0.34
HTT P42858 1/20 0.34
NOTUM Q6P988 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
ADORA3 P0DMS8 2/20 0.33
ADORA2A P29274 2/20 0.33
ADORA2B P29275 2/20 0.33
ADORA1 P30542 2/20 0.33
POLB P06746 2/20 0.33
PRNP P04156 1/20 0.33
KDM4E B2RXH2 2/20 0.33
TSHR P16473 2/20 0.33
ALOX15 P16050 1/20 0.33
NTSR1 P30989 1/20 0.33
PIK3CA P42336 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPK1 P28482 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL197197 0.87 MEN1 (0.42) MEN1KMT2AACP1HTTNOTUM
SCHEMBL15217962 0.87 MEN1 (0.37) MEN1KMT2AACP1HTTNOTUM
SCHEMBL18649110 0.78 KMT2A (0.39) MEN1KMT2AACP1HTTNOTUM
SCHEMBL487223 0.76 ADORA2A (0.58) MEN1KMT2AHTTADORA3ADORA2A
SCHEMBL469072 0.75 ACP1 (0.36) MEN1KMT2AACP1HTTNOTUM
SCHEMBL13140683 0.74 L3MBTL1 (0.38) MEN1KMT2AACP1HTTNOTUM
SCHEMBL12727235 0.74 POLB (0.48) MEN1KMT2AACP1NOTUML3MBTL1
SCHEMBL3623409 0.73 IDH1 (0.43) MEN1KMT2AACP1HTTNOTUM
SCHEMBL13140682 0.73 ACP1 (0.37) MEN1KMT2AACP1HTTNOTUM
SCHEMBL14123176 0.72 ALDH1A1 (0.40) MEN1KMT2AACP1HTTNOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9405206-B2 Electrophotographic photosensitive member and method of producing the electrophotographic photosensitive member, and process cartridge and electrophotographic apparatus each including the electrophotographic photosensitive member CANON KABUSHIKI KAISHA (JP) 2016-08-02 US disclosed
US-20150185639-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER AND METHOD OF PRODUCING THE ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, AND PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS EACH INCLUDING THE ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CANON KABUSHIKI KAISHA (JP) 2015-07-02 US disclosed