SCHEMBL1687773

SCHEMBL1687773

c1ccc(-c2cc(-c3cccc(-n4c5ccccc5c5cc(-n6c7ccccc7c7ccccc76)ccc54)c3)cc(-c3cccc4c3oc3ccccc34)c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.43
GGPS1 O95749 1/20 0.38
ATM Q13315 2/20 0.37
KDM4E B2RXH2 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
PRKDC P78527 7/20 0.36
PTGES2 Q9H7Z7 1/20 0.35
PRMT5 O14744 1/20 0.35
WDR77 Q9BQA1 1/20 0.35
PLA2G2A P14555 2/20 0.33
PLA2G4A P47712 2/20 0.33
PDE10A Q9Y233 1/20 0.32
ALDH1A1 P00352 2/20 0.32
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
TSHR P16473 1/20 0.32
BRCA1 P38398 1/20 0.32
KMT2A Q03164 1/20 0.32
HSD17B10 Q99714 1/20 0.32
PIK3CD O00329 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18020773 0.96 ALOX5 (0.45) ALOX5GGPS1ATMKDM4EL3MBTL1
SCHEMBL18020748 0.96 ALOX5 (0.45) ALOX5GGPS1ATMKDM4EL3MBTL1
SCHEMBL1687807 0.94 ALOX5 (0.48) ALOX5GGPS1ATMKDM4EL3MBTL1
SCHEMBL1687753 0.94 ALOX5 (0.48) ALOX5GGPS1ATMKDM4EL3MBTL1
SCHEMBL1687786 0.94 ALOX5 (0.48) ALOX5GGPS1ATMKDM4EL3MBTL1
SCHEMBL24303902 0.93 ALOX5 (0.48) ALOX5GGPS1ATMKDM4EL3MBTL1
SCHEMBL21578704 0.93 ALOX5 (0.48) ALOX5GGPS1ATMKDM4EL3MBTL1
SCHEMBL1687698 0.93 ALOX5 (0.47) ALOX5GGPS1ATMKDM4EL3MBTL1
SCHEMBL18020755 0.93 ALOX5 (0.47) ALOX5GGPS1ATMPRKDCPTGES2
SCHEMBL25138600 0.93 ALOX5 (0.48) ALOX5GGPS1ATMKDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9401482-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-07-26 US disclosed
US-9401482-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-07-26 US disclosed
US-20150097176-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-04-09 US disclosed
US-20150097176-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-04-09 US disclosed
US-8932734-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-01-13 US disclosed
US-8932734-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-01-13 US disclosed
US-20120086329-A1 Novel 3, 9-Linked Oliogocarbazole-Based Hosts, Containing DBT and DBF Fragments, Separated by Aromatic Spacers Universal Disolay Corporation (US) 2012-04-12 US disclosed
US-20120086329-A1 Novel 3, 9-Linked Oliogocarbazole-Based Hosts, Containing DBT and DBF Fragments, Separated by Aromatic Spacers Universal Disolay Corporation (US) 2012-04-12 US disclosed
WO-2012048266-A1 NOVEL 3, 9-LINKED OLIGOCARBAZOLE-BASED HOSTS, CONTAINING DBT AND DBR FRAGMENTS, SEPARATED BY AROMATIC SPACERS UNIVERSAL DISPLAY CORPORATION (US) 2012-04-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120086329-A1 Novel 3, 9-Linked Oliogocarbazole-Based Hosts, Containing DBT and DBF Fragments, Separated by Aromatic Spacers DBF4, OGFOD1, DDT ALOX5 1460/4885GGPS1 404/4885ATM 1916/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.