Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15257990 | 0.84 | SMN1; SMN2 (0.82) | MEN1KMT2ATRPV1SMN1; SMN2HDAC3 | |
| SCHEMBL5222902 | 0.84 | NR1H4 (0.67) | MEN1KMT2ATDP1TRPV1PPARG | |
| SCHEMBL1687877 | 0.83 | SMO (0.73) | TRPV1SMN1; SMN2HDAC3HDAC11HDAC8 | |
| SCHEMBL7303163 | 0.83 | HDAC3 (0.86) | MEN1KMT2ATRPV1SMN1; SMN2LMNA | |
| SCHEMBL12334059 | 0.82 | MEN1 (0.67) | MEN1KMT2ATDP1SMN1; SMN2LMNA | |
| SCHEMBL1687868 | 0.82 | TRPV1 (0.76) | MEN1KMT2ATRPV1SMN1; SMN2HDAC3 | |
| SCHEMBL21652312 | 0.82 | TRPV1 (0.76) | MEN1KMT2ATRPV1SMN1; SMN2HDAC3 | |
| SCHEMBL7301130 | 0.82 | TRPV1 (0.76) | MEN1KMT2ATRPV1SMN1; SMN2HDAC3 | |
| SCHEMBL6816843 | 0.81 | KMT2A (0.55) | MEN1KMT2ATDP1TRPV1SMN1; SMN2 | |
| SCHEMBL7302565 | 0.81 | KCNK9 (0.76) | MEN1KMT2ATRPV1SMN1; SMN2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130245275-A1 | PHENYL DIAMIDES AND A PHARMACEUTICAL PREPARATION COMPRISING PHENYL DIAMIDES | RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITAET BONN (DE) | 2013-09-19 | — | — | US | disclosed |
| US-20130245275-A1 | PHENYL DIAMIDES AND A PHARMACEUTICAL PREPARATION COMPRISING PHENYL DIAMIDES | RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITAET BONN (DE) | 2013-09-19 | — | — | US | disclosed |
| WO-2012045734-A1 | PHENYL DIAMIDES AND A PHARMACEUTICAL PREPARATION COMPRISING PHENYL DIAMIDES | RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITÄT (DE) | 2012-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130245275-A1 | PHENYL DIAMIDES AND A PHARMACEUTICAL PREPARATION COMPRISING PHENYL DIAMIDES | QDPR, DDT, DDC | MEN1 327/4885KMT2A 1017/4885TDP1 373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.