Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 11/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16880061 | 0.83 | GRM5 (0.40) | GRM5ALBHSD11B1 | |
| SCHEMBL16880046 | 0.80 | ALDH1A1 (0.43) | GRM5ALDH1A1MAPK1MAPTKDM4E | |
| SCHEMBL31318725 | 0.78 | GRM5 (0.48) | GRM5ALDH1A1MAPK1MAPTALOX5 | |
| SCHEMBL16880063 | 0.78 | ALB (0.39) | GRM5ALBHSD11B1 | |
| SCHEMBL16799127 | 0.74 | NPC1 (0.42) | GRM5MAPTALOX5ALBMEN1 | |
| SCHEMBL6893699 | 0.73 | GRM5 (0.63) | GRM5ALDH1A1MAPK1 | |
| SCHEMBL16799586 | 0.73 | GRM5 (0.44) | GRM5ALDH1A1MAPTALOX5ALB | |
| SCHEMBL16879820 | 0.73 | DRD2 (0.54) | DRD2DRD3GRM5ALDH1A1MAPK1 | |
| SCHEMBL16888073 | 0.73 | WNT3A (0.42) | GRM5ALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL31573909 | 0.73 | GRM5 (0.63) | GRM5ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015101928-A1 | FUSED THIOPHENE AND THIAZOLE DERIVATIVES AS ROR GAMMA MODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2015-07-09 | — | — | WO | disclosed |
| WO-2015101928-A1 | FUSED THIOPHENE AND THIAZOLE DERIVATIVES AS ROR GAMMA MODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2015-07-09 | — | — | WO | disclosed |