Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15160053 | 0.89 | POLB (0.38) | KDM4ESMN1; SMN2HSD17B10ALDH1A1HPGD | |
| SCHEMBL1688170 | 0.82 | PIK3CA (0.38) | KDM4EHSD17B10ALDH1A1HPGDTP53 | |
| SCHEMBL15494629 | 0.80 | LMNA (0.37) | KDM4ESMN1; SMN2HSD17B10ALDH1A1HPGD | |
| SCHEMBL15158632 | 0.78 | MAPT (0.36) | KDM4ESMN1; SMN2HSD17B10ALDH1A1HPGD | |
| SCHEMBL10010044 | 0.77 | PIK3CA (0.39) | KDM4EALDH1A1TP53POLBMEN1 | |
| SCHEMBL1708185 | 0.74 | ALDH1A1 (0.37) | KDM4EHSD17B10ALDH1A1HPGDPOLB | |
| SCHEMBL1708215 | 0.73 | ALDH1A1 (0.36) | KDM4EHSD17B10ALDH1A1HPGDPOLB | |
| SCHEMBL10291211 | 0.71 | MTOR (0.34) | KDM4ESMN1; SMN2HSD17B10ALDH1A1HPGD | |
| SCHEMBL13517804 | 0.71 | LMNA (0.40) | KDM4ESMN1; SMN2HSD17B10ALDH1A1HPGD | |
| SCHEMBL3717000 | 0.71 | MAPT (0.34) | KDM4ESMN1; SMN2HSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150225392-A1 | CYCLIC AMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2015-08-13 | — | — | US | disclosed |
| WO-2012046869-A1 | CYCLIC AMIDE DERIVATIVE | 持田製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150225392-A1 | CYCLIC AMIDE DERIVATIVE | GPR119, NR0B1, NR2C2 | KDM4E 2989/4885SMN1; SMN2 3209/4885HSD17B10 229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.