Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | C5AR1 | P21730 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15160352 | 0.86 | SLC6A2 (0.43) | SLC6A2SLC6A4MAPTTDP1MAPK1 | |
| SCHEMBL15158792 | 0.81 | SLC6A2 (0.40) | SLC6A2SLC6A4MAPTTDP1MAPK1 | |
| SCHEMBL23555133 | 0.79 | SLC6A2 (0.50) | SLC6A2SLC6A4MAPTTDP1MAPK1 | |
| SCHEMBL15495294 | 0.79 | GRM2 (0.43) | MAPTTDP1MAPK1GAAATM | |
| SCHEMBL1688137 | 0.78 | SLC6A2 (0.44) | SLC6A2SLC6A4MAPTTDP1MAPK1 | |
| SCHEMBL15160355 | 0.78 | MAP4K4 (0.44) | SLC6A2SLC6A4MAPTTDP1MAPK1 | |
| SCHEMBL21287875 | 0.73 | ALDH1A1 (0.42) | SLC6A2SLC6A4MAPTTDP1MAPK1 | |
| SCHEMBL23554912 | 0.73 | SLC6A2 (0.38) | SLC6A2SLC6A4MAPTTDP1MAPK1 | |
| SCHEMBL15158612 | 0.73 | C5AR1 (0.38) | SLC6A2SLC6A4MAPTC5AR1HTT | |
| SCHEMBL28263429 | 0.72 | HRH3 (0.48) | SLC6A2SLC6A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9072758-B2 | Cyclic amide derivative | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2015-07-07 | — | — | US | disclosed |