Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | C5AR1 | P21730 | 13/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23554912 | 0.82 | SLC6A2 (0.38) | ALDH1A1SMN1; SMN2TDP1KDM4EMAPT | |
| SCHEMBL23555133 | 0.79 | SLC6A2 (0.50) | ALDH1A1TDP1KDM4EMAPTMAPK1 | |
| SCHEMBL1688137 | 0.75 | SLC6A2 (0.44) | ALDH1A1SMN1; SMN2TDP1KDM4EMAPT | |
| SCHEMBL15160352 | 0.74 | SLC6A2 (0.43) | ALDH1A1SMN1; SMN2TDP1KDM4EMAPT | |
| SCHEMBL16882199 | 0.73 | SLC6A2 (0.43) | ALDH1A1SMN1; SMN2TDP1KDM4EMAPT | |
| SCHEMBL27307706 | 0.73 | SLC6A2 (0.42) | ALDH1A1MAPTMAPK1C5AR1SLC6A2 | |
| SCHEMBL19019196 | 0.72 | KMT2A (0.39) | TDP1MAPTC5AR1MEN1KMT2A | |
| SCHEMBL16998574 | 0.72 | KMT2A (0.39) | TDP1MAPTC5AR1MEN1KMT2A | |
| SCHEMBL18064932 | 0.71 | LMNA (0.51) | C5AR1SLC6A2SLC6A4KMT2A | |
| SCHEMBL18064812 | 0.70 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2TDP1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190256494-A1 | PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | H. LUNDBECK A/S (DK) | 2019-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190256494-A1 | PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ABHD6, ABHD16A, RABL6 | ALDH1A1 1812/4885SMN1; SMN2 2914/4885TDP1 2125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.