Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | IL1B | P01584 | 9/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.38 |
| ▸ | SCD | O00767 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13212627 | 0.90 | CNR2 (0.43) | CNR2IL1BNLRP3SCDRAB9A | |
| SCHEMBL13212724 | 0.87 | SCD (0.42) | CNR2IL1BNLRP3SCDRAB9A | |
| SCHEMBL13212824 | 0.86 | IL1B (0.42) | CNR2IL1BNLRP3SCD | |
| SCHEMBL13212643 | 0.86 | CNR2 (0.56) | CNR2SCDRAB9AMEN1KMT2A | |
| SCHEMBL1740036 | 0.84 | LMNA (0.46) | CNR2SCDRAB9AMEN1KMT2A | |
| SCHEMBL13212838 | 0.79 | CCR2 (0.43) | CNR2IL1BSCDRAB9AMEN1 | |
| SCHEMBL13212639 | 0.78 | CCR2 (0.42) | IL1BNLRP3SCDRAB9ANPC1 | |
| SCHEMBL13212816 | 0.77 | LMNA (0.42) | RAB9ANPC1MAPTLMNATHRB | |
| SCHEMBL13212613 | 0.76 | CCR2 (0.50) | RAB9ANPC1 | |
| SCHEMBL13212808 | 0.76 | HTR6 (0.40) | SCDRAB9AMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155689-B1 | CCR2 RECEPTOR ANTAGONISTS AND USES THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2015-07-08 | — | — | EP | disclosed |