Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18626392 | 0.88 | LMNA (0.44) | GPR3MAPTALDH1A1HPGDL3MBTL1 | |
| SCHEMBL24223787 | 0.83 | LMNA (0.34) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL20708376 | 0.81 | GPR3 (0.39) | GPR3KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL22596755 | 0.80 | L3MBTL1 (0.34) | GPR3KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL19275598 | 0.80 | GPR3 (0.38) | GPR3KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL23204779 | 0.78 | TDP1 (0.33) | GPR3MAPTALDH1A1HPGDL3MBTL1 | |
| SCHEMBL19860208 | 0.77 | GPR3 (0.48) | GPR3KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL18323686 | 0.76 | GPR3 (0.44) | GPR3KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL19365233 | 0.75 | GPR3 (0.50) | GPR3KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL18874657 | 0.75 | ALDH1A1 (0.43) | GPR3KDM4EMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150194622-A1 | BISCARBAZOLE DERIVATIVE HOST MATERIALS AND RED EMITTER FOR OLED EMISSIVE REGION | IDEMITSU KOSAN CO., LTD. (JP) | 2015-07-09 | — | — | US | disclosed |
| US-8962638-B2 | Piperidine inhibitors of janus kinase 3 | AUSPEX PHARMACEUTICALS, INC. (US) | 2015-02-24 | — | — | US | disclosed |