Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.69 |
| ▸ | RECQL | P46063 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.69 |
| ▸ | SOST | Q9BQB4 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.62 |
| ▸ | SLCO1B3 | Q9NPD5 | 4/20 | 0.62 |
| ▸ | SLCO1B1 | Q9Y6L6 | 4/20 | 0.62 |
| ▸ | SLCO2B1 | O94956 | 3/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16884531 | 0.91 | CYP3A4 (0.69) | CYP3A4ALOX15MAPTHSD17B10RECQL | |
| Dihydroisorhamnetin SCHEMBL16887921 | 0.87 | CYP2C9 (0.78) | CYP3A4ALOX15MAPTHSD17B10RECQL | |
| Dihydroisorhamnetin SCHEMBL30915472 | 0.87 | CYP2C9 (0.78) | CYP3A4ALOX15MAPTHSD17B10RECQL | |
| Dihydroisorhamnetin SCHEMBL31237482 | 0.87 | CYP2C9 (0.78) | CYP3A4ALOX15MAPTHSD17B10RECQL | |
| Dihydroisorhamnetin SCHEMBL30255782 | 0.87 | CYP2C9 (0.78) | CYP3A4ALOX15MAPTHSD17B10RECQL | |
| SCHEMBL23353527 | 0.87 | CYP3A4 (0.69) | CYP3A4ALOX15MAPTHSD17B10RECQL | |
| SCHEMBL16884474 | 0.87 | CYP3A4 (0.69) | CYP3A4ALOX15MAPTHSD17B10RECQL | |
| SCHEMBL19789557 | 0.85 | XDH (0.70) | CYP3A4ALOX15MAPTHSD17B10RECQL | |
| SCHEMBL16884478 | 0.83 | CYP3A4 (0.70) | CYP3A4ALOX15MAPTHSD17B10RECQL | |
| SCHEMBL23353528 | 0.83 | CYP3A4 (0.70) | CYP3A4ALOX15MAPTHSD17B10RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150191430-A1 | CONJUGATES OF HUPERZINE AND ANALOGS THEREOF | BISCAYNE NEUROTHERAPEUTICS, INC. | 2015-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150191430-A1 | CONJUGATES OF HUPERZINE AND ANALOGS THEREOF | HTT, HNMT, GAP43 | CYP3A4 2126/4885ALOX15 686/4885MAPT 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.