Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | TDO2 | P48775 | 2/20 | 0.44 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.44 |
| ▸ | MAT2A | P31153 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1688906 | 0.89 | TDO2 (0.45) | CNR1TDO2IDO2MAT2AALDH1A1 | |
| SCHEMBL1688973 | 0.87 | KDM4E (0.46) | CNR1IDO1TDO2IDO2ALDH1A1 | |
| SCHEMBL5611633 | 0.83 | MAPT (0.43) | CNR1ALDH1A1CYP1A2HSD17B10CYP2C9 | |
| SCHEMBL1688941 | 0.83 | PTGS2 (0.41) | ALDH1A1CYP1A2HSD17B10CYP2C9MAPK1 | |
| SCHEMBL1688982 | 0.81 | KDM4E (0.43) | CNR1MAPK1KDM4ECNR2 | |
| SCHEMBL5611689 | 0.81 | KDM4E (0.43) | CNR1IDO1TDO2IDO2MAT2A | |
| SCHEMBL1753297 | 0.80 | MAPT (0.61) | ALDH1A1LMNASMN1; SMN2KDM4EHPGD | |
| SCHEMBL1688942 | 0.78 | CNR1 (0.43) | CNR1MAT2AMAPK1KDM4EKMT2A | |
| SCHEMBL5611629 | 0.77 | SMN1; SMN2 (0.41) | CNR1ALDH1A1CYP1A2HSD17B10CYP2C9 | |
| SCHEMBL5611704 | 0.76 | CNR1 (0.45) | CNR1MAPK1KDM4EKMT2ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807429-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM, LLC (BM) | 2007-07-18 | — | — | EP | claimed |
| WO-2006047516-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2006-05-04 | — | — | WO | claimed |