Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | ALDH1A2 | O94788 | 4/20 | 0.43 |
| ▸ | ALDH1A3 | P47895 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1753246 | 0.79 | GRM1 (0.58) | ALDH1A1KMT2AMAPTHPGDGRM1 | |
| SCHEMBL1689243 | 0.78 | MAPT (0.51) | ALDH1A1MEN1KMT2AMAPTHSP90AA1 | |
| SCHEMBL1688901 | 0.76 | ALDH1A1 (0.42) | ALDH1A1ALDH1A2ALDH1A3MEN1KMT2A | |
| SCHEMBL5611687 | 0.74 | MAPT (0.52) | ALDH1A1MEN1KMT2AMAPTHSP90AA1 | |
| SCHEMBL1689094 | 0.74 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2AMAPTHSP90AA1 | |
| SCHEMBL5612533 | 0.73 | MAPT (0.45) | ALDH1A1MEN1KMT2AMAPTHSP90AA1 | |
| SCHEMBL1689138 | 0.72 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AMAPTHSP90AA1 | |
| SCHEMBL1689133 | 0.72 | MAPT (0.58) | ALDH1A1MEN1KMT2AMAPTHSP90AA1 | |
| SCHEMBL5611664 | 0.72 | MAPT (0.49) | ALDH1A1MEN1KMT2AMAPTHSP90AA1 | |
| SCHEMBL1689060 | 0.72 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AMAPTHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807429-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM, LLC (BM) | 2007-07-18 | — | — | EP | claimed |
| WO-2006047516-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2006-05-04 | — | — | WO | claimed |
| EP-1807429-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM, LLC (BM) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006047516-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2006-05-04 | — | — | WO | disclosed |