SCHEMBL16890215

SCHEMBL16890215

Cc1ccccc1-c1cccc(Oc2cccc(Oc3cccc(-c4ccccc4C)c3)c2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 3/20 0.49
HTR1A P08908 1/20 0.44
CASR P41180 1/20 0.44
FFAR1 O14842 4/20 0.41
FFAR4 Q5NUL3 1/20 0.41
GSTP1 P09211 1/20 0.40
MCL1 Q07820 1/20 0.40
CNR1 P21554 1/20 0.40
MEN1 O00255 1/20 0.39
MITF O75030 1/20 0.39
ALDH1A1 P00352 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
GFER P55789 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NLRP1 Q9C000 1/20 0.39
NOD2 Q9HC29 1/20 0.39
CYP1A1 P04798 1/20 0.39
CYP1A2 P05177 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11344051 0.98 HTR7 (0.50) HTR7HTR1ACASRFFAR1FFAR4
SCHEMBL321834 0.85 CASR (0.57) HTR7CASRALDH1A1CYP1A1CYP1A2
Diphenylether SCHEMBL9751558 0.82 LTA4H (0.52) GSTP1ALDH1A1SMN1; SMN2CYP2A6CYP2B6
Methyl Alcohol SCHEMBL27555715 0.81 CASR (0.54) HTR7CASRALDH1A1CYP1A1CYP1A2
SCHEMBL29628983 0.81 HTR7 (0.60) HTR7HTR1AMCL1CNR1ALDH1A1
SCHEMBL19577765 0.81 HTR7 (0.60) HTR7HTR1AMCL1CNR1ALDH1A1
SCHEMBL6313369 0.80 BRD4 (0.50) HTR7CASRFFAR1FFAR4ALDH1A1
SCHEMBL964683 0.80 RXRA (0.50) HTR7HTR1ACASRFFAR1FFAR4
SCHEMBL9461753 0.79 GSTP1 (0.55) FFAR1FFAR4GSTP1MEN1MITF
SCHEMBL11753055 0.79 GSTP1 (0.55) FFAR1FFAR4GSTP1MEN1MITF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3109253-B1 POLYCYCLIC AROMATIC COMPOUNDS AND THEIR USE AS ORGANIC DEVICE MATERIAL KWANSEI GAKUIN EDUCATIONAL FOUND (JP) 2018-10-24 EP disclosed
EP-3345911-A1 POLYCYCLIC AROMATIC COMPOUNDS AND THEIR USE AS ORGANIC DEVICE MATERIAL Kwansei Gakuin Educational Foundation (JP) 2018-07-11 EP disclosed
EP-3345911-A1 POLYCYCLIC AROMATIC COMPOUNDS AND THEIR USE AS ORGANIC DEVICE MATERIAL Kwansei Gakuin Educational Foundation (JP) 2018-07-11 EP disclosed
EP-3109253-A1 POLYCYCLIC AROMATIC COMPOUND Kwansei Gakuin Educational Foundation (JP) 2016-12-28 EP disclosed
WO-2015102118-A1 POLYCYCLIC AROMATIC COMPOUND 学校法人関西学院 2015-07-09 WO disclosed