Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 10/20 | 0.71 |
| ▸ | SLC9A1 | P19634 | 4/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.51 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2734889 | 0.83 | GRM2 (1.00) | GRM2SLC9A1TDP1KDM4EALDH1A1 | |
| SCHEMBL12204547 | 0.80 | GRM2 (0.64) | GRM2SLC9A1TDP1CYP2C9KDM4E | |
| SCHEMBL18645646 | 0.78 | GRM2 (0.65) | GRM2SLC9A1TDP1CYP2C9KDM4E | |
| SCHEMBL22000732 | 0.78 | GRM2 (0.75) | GRM2SLC9A1TDP1KCNMA1PTK2 | |
| SCHEMBL28345673 | 0.78 | GRM2 (0.75) | GRM2SLC9A1TDP1KDM4EALDH1A1 | |
| SCHEMBL16398499 | 0.78 | GRM2 (0.75) | GRM2SLC9A1TDP1KDM4EKCNMA1 | |
| SCHEMBL7597659 | 0.78 | GRM2 (0.75) | GRM2SLC9A1TDP1CYP2C9KDM4E | |
| SCHEMBL15338669 | 0.74 | TDP1 (0.67) | GRM2SLC9A1TDP1CYP2C9PTK2 | |
| SCHEMBL24051506 | 0.73 | SLC9A1 (0.68) | GRM2SLC9A1TDP1KCNMA1PTK2 | |
| SCHEMBL24460754 | 0.73 | GRM2 (0.68) | GRM2SLC9A1TDP1ALDH1A1KCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015101293-A1 | KINASE INHIBITOR AND USE THEREOF | 山东轩竹医药科技有限公司 | 2015-07-09 | — | — | WO | disclosed |