Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 10/20 | 0.65 |
| ▸ | SLC9A1 | P19634 | 4/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.49 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2734889 | 0.80 | GRM2 (1.00) | GRM2SLC9A1TDP1KDM4EALDH1A1 | |
| SCHEMBL16892016 | 0.78 | GRM2 (0.71) | GRM2SLC9A1TDP1CYP2C9KDM4E | |
| SCHEMBL9305191 | 0.75 | GAA (0.66) | GRM2SLC9A1TDP1ALDH1A1PTK2 | |
| SCHEMBL30368818 | 0.75 | GAA (0.66) | GRM2SLC9A1TDP1ALDH1A1PTK2 | |
| SCHEMBL7597659 | 0.74 | GRM2 (0.75) | GRM2SLC9A1TDP1CYP2C9KDM4E | |
| SCHEMBL22000732 | 0.74 | GRM2 (0.75) | GRM2SLC9A1TDP1PTK2KCNMA1 | |
| SCHEMBL16398499 | 0.74 | GRM2 (0.75) | GRM2SLC9A1TDP1KDM4EKCNMA1 | |
| SCHEMBL28345673 | 0.74 | GRM2 (0.75) | GRM2SLC9A1TDP1KDM4EALDH1A1 | |
| SCHEMBL7599503 | 0.74 | SLC9A1 (0.69) | GRM2SLC9A1TDP1CYP2C9ALDH1A1 | |
| SCHEMBL9303448 | 0.74 | PTK2 (0.72) | GRM2SLC9A1TDP1ALDH1A1PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017042643-A1 | FLUOROINDOLE DERIVATIVES AS MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | SUVEN LIFE SCIENCES LIMITED (IN) | 2017-03-16 | — | — | WO | disclosed |