SCHEMBL16398499

SCHEMBL16398499

Oc1ccc(Cn2nnc3ccccc32)cc1

nearest known ligand 0.75

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ GRM2 Q14416 7/20 0.75
▸ SLC9A1 P19634 3/20 0.75
▸ TDP1 Q9NUW8 1/20 0.73
▸ RPS6KA3 P51812 1/20 0.63
▸ KCNMA1 Q12791 1/20 0.62
▸ KDM4E B2RXH2 1/20 0.54
▸ LMNA P02545 1/20 0.54
▸ TP53 P04637 1/20 0.54
▸ HSD17B10 Q99714 1/20 0.54
▸ NPC1 O15118 1/20 0.53
▸ MAPT P10636 1/20 0.53
▸ RAB9A P51151 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2734889 0.86 GRM2 (1.00) GRM2SLC9A1TDP1KCNMA1KDM4E
SCHEMBL7597659 0.83 GRM2 (0.75) GRM2SLC9A1TDP1KDM4E
SCHEMBL28345673 0.83 GRM2 (0.75) GRM2SLC9A1TDP1KCNMA1KDM4E
SCHEMBL22000732 0.83 GRM2 (0.75) GRM2SLC9A1TDP1KCNMA1LMNA
SCHEMBL10797939 0.81 HCAR3 (0.68) GRM2SLC9A1TDP1RPS6KA3KCNMA1
SCHEMBL28514074 0.80 GRM2 (0.65) GRM2SLC9A1TDP1KCNMA1KDM4E
SCHEMBL3651402 0.80 MAPT (0.61) GRM2SLC9A1TDP1RPS6KA3KCNMA1
SCHEMBL1764460 0.79 MAPT (0.60) GRM2SLC9A1TDP1RPS6KA3KCNMA1
SCHEMBL24051506 0.79 SLC9A1 (0.68) GRM2SLC9A1TDP1KCNMA1NPC1
SCHEMBL14376781 0.78 GRM2 (0.61) GRM2SLC9A1TDP1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110831569-B Photoprotective compositions 欧莱雅 2022-10-21 — — CN claimed
CN-114699328-A Photoprotective compositions 欧莱雅 2022-07-05 — — CN claimed
EP-3022273-B1 LIQUID CRYSTAL POLYMER COMPOSITION, METHOD FOR PREPARING SAME, AND LIQUID CRYSTAL ARTICLE COMPRISING SAME SAINT GOBAIN (FR) 2018-04-11 — — EP claimed
EP-3022273-A1 LIQUID CRYSTAL POLYMER COMPOSITION, METHOD FOR PREPARING SAME, AND LIQUID CRYSTAL ARTICLE COMPRISING SAME Saint-Gobain Glass France (FR) 2016-05-25 — — EP claimed
WO-2015007218-A1 LIQUID CRYSTAL POLYMER COMPOSITION, METHOD FOR PREPARING SAME, AND LIQUID CRYSTAL ARTICLE COMPRISING SAME SAINT-GOBAIN GLASS FRANCE (FR) 2015-01-22 — — WO claimed
CN-110831569-B Photoprotective compositions 欧莱雅 2022-10-21 — — CN disclosed
CN-114699328-A Photoprotective compositions 欧莱雅 2022-07-05 — — CN disclosed
CN-107750161-B Composition for preventing or treating inflammatory diseases comprising extracellular vesicles derived from lactic acid bacteria as active ingredient MD保健株式会社 2022-01-14 — — CN disclosed
EP-3022273-B1 LIQUID CRYSTAL POLYMER COMPOSITION, METHOD FOR PREPARING SAME, AND LIQUID CRYSTAL ARTICLE COMPRISING SAME SAINT GOBAIN (FR) 2018-04-11 — — EP disclosed
EP-3022273-A1 LIQUID CRYSTAL POLYMER COMPOSITION, METHOD FOR PREPARING SAME, AND LIQUID CRYSTAL ARTICLE COMPRISING SAME Saint-Gobain Glass France (FR) 2016-05-25 — — EP disclosed
WO-2015007218-A1 LIQUID CRYSTAL POLYMER COMPOSITION, METHOD FOR PREPARING SAME, AND LIQUID CRYSTAL ARTICLE COMPRISING SAME SAINT-GOBAIN GLASS FRANCE (FR) 2015-01-22 — — WO disclosed
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