Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 7/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | STK17B | O94768 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 3/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | CTSA | P10619 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14408027 | 0.79 | KCNH2 (0.52) | DYRK1AKCNH2SCN10ASTK17BKCNA5 | |
| SCHEMBL5358364 | 0.79 | KCNH2 (0.52) | DYRK1AKCNH2SCN10ASTK17BKCNA5 | |
| SCHEMBL16886210 | 0.79 | LOXL2 (0.50) | LOXL2STK17B | |
| SCHEMBL2226631 | 0.77 | LOXL2 (0.58) | LOXL2 | |
| SCHEMBL16886211 | 0.76 | LOXL2 (0.50) | LOXL2 | |
| SCHEMBL4508943 | 0.74 | HDAC6 (0.42) | DYRK1ALOXL2STK17B | |
| SCHEMBL22042127 | 0.73 | FEN1 (0.43) | KCNH2SCN10ALOXL2CTSA | |
| SCHEMBL2560013 | 0.72 | MLYCD (0.54) | DYRK1AKCNH2SCN10APIM1 | |
| SCHEMBL5274981 | 0.70 | MAPK14 (0.47) | DYRK1AKCNH2SCN10ASTK17BCTSA | |
| SCHEMBL19992641 | 0.69 | KCNH2 (0.51) | DYRK1AKCNH2SCN10ANPY5RPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150191420-A1 | ANTIBACTERIAL AGENTS | TAXIS PHARMACEUTICALS, INC. | 2015-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150191420-A1 | ANTIBACTERIAL AGENTS | ALK, ARG1, ROS1 | DYRK1A 3576/4885KCNH2 143/4885SCN10A 2625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.