SCHEMBL16892201

SCHEMBL16892201

CC[C@H](NCc1cccc(COc2ccc3c(c2)OCO3)c1)C(N)=O

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAOB P27338 10/20 0.52
MAOA P21397 6/20 0.52
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
SCN9A Q15858 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16892175 0.88 MAOB (0.60) MAOBMAOANPC1RAB9ASCN9A
SCHEMBL16892177 0.88 MAOB (0.60) MAOBMAOANPC1RAB9ASCN9A
SCHEMBL16892155 0.86 MAOB (0.52) MAOBMAOANPC1RAB9ASCN9A
SCHEMBL16892164 0.82 ALDH1A1 (0.47) NPC1RAB9ASCN9A
SCHEMBL16892162 0.80 SPHK2 (0.58) MAOBMAOANPC1RAB9A
SCHEMBL16892163 0.78 MAOB (0.57) MAOBMAOANPC1RAB9ASCN9A
SCHEMBL5133922 0.76 MAOB (0.76) MAOBMAOASCN9A
SCHEMBL16892156 0.75 KDM4E (0.51) MAOBMAOASCN9A
SCHEMBL7398312 0.75 MAOB (0.55) MAOBMAOASCN9A
SCHEMBL8935385 0.75 MAOB (0.55) MAOBMAOASCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015101294-A1 COMPOUNDS WITH ANALGESIC ACTIVITY AND MEDICAL USE THEREOF 中国人民解放军军事医学科学院毒物药物研究所 2015-07-09 WO disclosed