Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16894629 | 0.87 | CYP19A1 (0.52) | CYP19A1KDM4EALDH1A1ABCG2MAPK1 | |
| SCHEMBL16894635 | 0.81 | ALDH1A1 (0.63) | CYP19A1KDM4EALDH1A1ABCG2MAPK1 | |
| SCHEMBL6723899 | 0.79 | MAOB (0.62) | CYP19A1KDM4EALDH1A1ABCG2MAPK1 | |
| SCHEMBL2879029 | 0.79 | ABCG2 (0.67) | CYP19A1KDM4EALDH1A1ABCG2MAPK1 | |
| SCHEMBL5085606 | 0.76 | CYP19A1 (0.63) | CYP19A1KDM4EALDH1A1ABCG2MAPK1 | |
| SCHEMBL29286014 | 0.74 | TAS2R31 (0.55) | CYP19A1KDM4EALDH1A1ABCG2MAPK1 | |
| SCHEMBL30989212 | 0.74 | TAS2R31 (0.55) | CYP19A1KDM4EALDH1A1ABCG2MAPK1 | |
| SCHEMBL16894664 | 0.74 | MAOB (0.60) | CYP19A1ABCG2CYP3A4MAPTABCB1 | |
| SCHEMBL16894614 | 0.73 | PTAFR (0.49) | CYP19A1KDM4EALDH1A1ABCG2MAPK1 | |
| SCHEMBL10425232 | 0.71 | ABCG2 (0.60) | CYP19A1KDM4EALDH1A1ABCG2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9669003-B2 | Use of flavone and flavanone derivatives in preparation of sedative and hypnotic drugs | JIN YONGRI (CN) | 2017-06-06 | — | — | US | claimed |
| US-20150196529-A1 | USE OF FLAVONE AND FLAVANONE DERIVATIVES IN PREPARATION OF SEDATIVE AND HYPNOTIC DRUGS | JIN YONGRI (CN) | 2015-07-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150196529-A1 | USE OF FLAVONE AND FLAVANONE DERIVATIVES IN PREPARATION OF SEDATIVE AND HYPNOTIC DRUGS | CYP2D6, GATAD2A, CYP3A43 | CYP19A1 1387/4885KDM4E 437/4885ALDH1A1 668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.