Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1053629 | 1.00 | ALDH1A1 (0.71) | ALDH1A1LMNATDP1TSHRCYP3A4 | |
| SCHEMBL14086791 | 1.00 | ALDH1A1 (0.71) | ALDH1A1LMNATDP1TSHRCYP3A4 | |
| Hydrochloric Acid SCHEMBL30829332 | 0.97 | ALDH1A1 (0.68) | ALDH1A1LMNATDP1TSHRCYP3A4 | |
| SCHEMBL15936481 | 0.95 | LMNA (0.81) | ALDH1A1LMNATDP1TSHRCYP3A4 | |
| SCHEMBL317382 | 0.94 | ALDH1A1 (0.79) | ALDH1A1LMNATDP1TSHRCYP3A4 | |
| SCHEMBL4806050 | 0.92 | LMNA (0.85) | ALDH1A1LMNATSHRCYP3A4FDPS | |
| SCHEMBL17526461 | 0.92 | LMNA (0.85) | ALDH1A1LMNATSHRCYP3A4FDPS | |
| SCHEMBL21366 | 0.92 | LMNA (0.85) | ALDH1A1LMNATSHRCYP3A4FDPS | |
| SCHEMBL25210796 | 0.90 | LMNA (0.90) | ALDH1A1LMNATSHRCYP3A4FDPS | |
| SCHEMBL15936482 | 0.90 | LMNA (0.90) | ALDH1A1LMNATSHRCYP3A4FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3764821-A1 | FOAM CONTROL | Dow Global Technologies, LLC (US) | 2021-01-20 | — | — | EP | disclosed |
| WO-2019177726-A1 | FOAM CONTROL | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-09-19 | — | — | WO | disclosed |
| US-10000432-B2 | Processes for the synthesis of chiral 1-alkanols | PURDUE RESEARCH FOUNDATION (US) | 2018-06-19 | — | — | US | disclosed |
| US-10000432-B2 | Processes for the synthesis of chiral 1-alkanols | PURDUE RESEARCH FOUNDATION (US) | 2018-06-19 | — | — | US | disclosed |
| EP-3094613-A1 | PROCESSES FOR THE SYNTHESIS OF CHIRAL 1-ALKANOLS | Purdue Research Foundation, Inc. (US) | 2016-11-23 | — | — | EP | disclosed |
| US-20160332940-A1 | PROCESSES FOR THE SYNTHESIS OF CHIRAL 1-ALKANOLS | PURDUE RESEARCH FOUNDATION (US) | 2016-11-17 | — | — | US | disclosed |
| US-20160332940-A1 | PROCESSES FOR THE SYNTHESIS OF CHIRAL 1-ALKANOLS | PURDUE RESEARCH FOUNDATION (US) | 2016-11-17 | — | — | US | disclosed |
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2016-02-11 | — | — | US | disclosed |
| WO-2015106045-A1 | PROCESSES FOR THE SYNTHESIS OF CHIRAL 1-ALKANOLS | PURDUE RESEARCH FOUNDATION (US) | 2015-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160332940-A1 | PROCESSES FOR THE SYNTHESIS OF CHIRAL 1-ALKANOLS | CYP51A1, ALKBH3, ALKBH1 | ALDH1A1 500/4885LMNA 3812/4885TDP1 3562/4885 |
| US-10000432-B2 | Processes for the synthesis of chiral 1-alkanols | CYP51A1, ALKBH3, ALKBH1 | ALDH1A1 500/4885LMNA 3812/4885TDP1 3562/4885 |
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | FKBP1B, MALT1, FKBP5 | ALDH1A1 2376/4885LMNA 3497/4885TDP1 1618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.