Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13970787 | 0.78 | KDM4E (0.35) | KDM4EGAAHRH4HRH3 | |
| SCHEMBL1199229 | 0.77 | — | — | |
| SCHEMBL16897951 | 0.71 | NOS2 (0.42) | HRH3 | |
| SCHEMBL13970742 | 0.70 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL29794191 | 0.68 | NOS2 (0.40) | KDM4EHRH4HRH3 | |
| SCHEMBL1040322 | 0.64 | — | — | |
| SCHEMBL29794166 | 0.63 | ALDH1A1 (0.48) | — | |
| SCHEMBL6591545 | 0.63 | GABRA5 (0.41) | KDM4EGAA | |
| SCHEMBL5469222 | 0.61 | TAAR1 (0.47) | KDM4EGAAHRH3 | |
| SCHEMBL29794154 | 0.61 | ALDH1A1 (0.43) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092255-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING EGFR EXPRESSING TUMORS | Birdie Biopharmaceuticals Inc. (KY) | 2016-11-16 | — | — | EP | disclosed |
| WO-2015103990-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING EGFR EXPRESSING TUMORS | SHANGHAI BIRDIE BIOTECH, INC. (CN) | 2015-07-16 | — | — | WO | disclosed |