Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16900219 | 0.94 | ALDH1A1 (0.42) | GAAHTTALDH1A1SMN1; SMN2SMYD3 | |
| SCHEMBL14424599 | 0.84 | HTT (0.59) | GAAHTTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL19022014 | 0.81 | ALDH1A1 (0.37) | GAAHTTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL1675808 | 0.81 | SMN1; SMN2 (0.40) | GAAHTTALDH1A1SMN1; SMN2SMYD3 | |
| SCHEMBL21349220 | 0.81 | HTT (0.42) | GAAHTTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL20960384 | 0.80 | HPGD (0.45) | GAAHTTALDH1A1KDM4EKMT2A | |
| SCHEMBL15630655 | 0.80 | HPGD (0.45) | GAAHTTALDH1A1KDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL6039736 | 0.80 | GNAI3 (0.41) | HTTALDH1A1SMN1; SMN2SMYD3KDM4E | |
| SCHEMBL16900216 | 0.80 | GAA (0.46) | GAAALDH1A1SMYD3KDM4EKMT2A | |
| SCHEMBL13180364 | 0.79 | SMYD3 (0.44) | GAAHTTALDH1A1SMN1; SMN2SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2861577-B1 | TERTIARY AMINES, MEDICAMENTS CONTAINING SAID AMINES, USE THEREOF AND PROCESSES FOR THE PREPARATION THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2017-01-04 | — | — | EP | disclosed |
| US-9078909-B2 | Tertiary amines, medicaments containing said amines, use thereof and processes for the preparation thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-07-14 | — | — | US | disclosed |