Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15630655 | 1.00 | HPGD (0.45) | HPGDALDH1A1BCHEMAPK1KDM4E | |
| SCHEMBL19022014 | 0.83 | ALDH1A1 (0.37) | HPGDALDH1A1MAPK1TDP1SIGMAR1 | |
| SCHEMBL16900211 | 0.80 | GAA (0.44) | ALDH1A1KDM4ETDP1SIGMAR1GAA | |
| SCHEMBL27711029 | 0.79 | HPGD (0.43) | HPGDALDH1A1BCHEMAPK1KDM4E | |
| SCHEMBL12226502 | 0.78 | HRH2 (0.37) | HPGDALDH1A1BCHEKDM4EL3MBTL1 | |
| SCHEMBL12226495 | 0.78 | HRH2 (0.37) | HPGDALDH1A1BCHEKDM4EL3MBTL1 | |
| SCHEMBL16900219 | 0.78 | ALDH1A1 (0.42) | ALDH1A1KDM4EL3MBTL1TDP1SIGMAR1 | |
| SCHEMBL14306830 | 0.78 | SMN1; SMN2 (0.40) | HPGDALDH1A1BCHEKDM4EL3MBTL1 | |
| SCHEMBL8023138 | 0.77 | ALDH1A1 (0.67) | ALDH1A1KDM4EL3MBTL1TDP1SIGMAR1 | |
| SCHEMBL19010425 | 0.77 | ALDH1A1 (0.61) | ALDH1A1KDM4EL3MBTL1TDP1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2897940-B1 | HETEROCYCLIC COMPOUNDS, MEDICAMENTS CONTAINING SAID COMPOUNDS, USE THEREOF AND PROCESSES FOR THE PREPARATION THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2019-05-01 | — | — | EP | disclosed |