Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1691121 | 0.92 | MAPK1 (0.40) | MAPK1KDM4EKMT2AATML3MBTL1 | |
| SCHEMBL19216705 | 0.92 | SMN1; SMN2 (0.41) | MAPK1KDM4EKMT2AATML3MBTL1 | |
| SCHEMBL19601350 | 0.91 | MAPK1 (0.37) | MAPK1KDM4EKMT2AATML3MBTL1 | |
| SCHEMBL15106626 | 0.91 | MAPK1 (0.37) | MAPK1KDM4EKMT2AATML3MBTL1 | |
| SCHEMBL23135868 | 0.90 | MAPK1 (0.39) | MAPK1KDM4EKMT2AATML3MBTL1 | |
| SCHEMBL13269316 | 0.87 | OPRM1 (0.48) | MAPK1KDM4EKMT2AATML3MBTL1 | |
| SCHEMBL23135867 | 0.87 | TSHR (0.43) | MAPK1KDM4EKMT2AATML3MBTL1 | |
| SCHEMBL17682272 | 0.87 | ALDH1A1 (0.39) | MAPK1KDM4EKMT2AATML3MBTL1 | |
| SCHEMBL5949120 | 0.86 | POLB (0.38) | MAPK1KDM4EKMT2AATML3MBTL1 | |
| SCHEMBL17682268 | 0.85 | TP53 (0.37) | MAPK1KDM4EKMT2AATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2894151-A1 | IMIDAZOLINE DERIVATIVES, PREPARATION METHODS THEREOF, AND THEIR APPLICATIONS IN MEDICINE | Shanghai Hengrui Pharmaceutical Co. Ltd. (CN) | 2015-07-15 | — | — | EP | disclosed |
| CN-1226886-A | Arylcycloalkane carboxylic acid esters, their use, pharmaceutical compositions and process for their preparation | PHARMACIA & UPJOHN AB (SE) | 1999-08-25 | — | — | CN | disclosed |