SCHEMBL1691121

SCHEMBL1691121

CCOC(=O)C1(COC)CCCC1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.40
CYP4F2 P78329 1/20 0.39
CYP4A11 Q02928 1/20 0.39
KDM4E B2RXH2 3/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
POLB P06746 3/20 0.36
KMT2A Q03164 5/20 0.36
MEN1 O00255 4/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
MAPT P10636 1/20 0.36
ATM Q13315 1/20 0.36
ALDH1A1 P00352 3/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23135868 0.98 MAPK1 (0.39) MAPK1CYP4F2CYP4A11KDM4ESMN1; SMN2
SCHEMBL19216705 0.96 SMN1; SMN2 (0.41) MAPK1CYP4F2CYP4A11KDM4ESMN1; SMN2
SCHEMBL16900591 0.92 MAPK1 (0.41) MAPK1KDM4ESMN1; SMN2POLBKMT2A
SCHEMBL15106626 0.84 MAPK1 (0.37) MAPK1KDM4ESMN1; SMN2POLBKMT2A
SCHEMBL19601350 0.84 MAPK1 (0.37) MAPK1KDM4ESMN1; SMN2POLBKMT2A
SCHEMBL13269316 0.84 OPRM1 (0.48) MAPK1KDM4EPOLBKMT2AMEN1
SCHEMBL23135867 0.84 TSHR (0.43) MAPK1KDM4EPOLBKMT2AMEN1
SCHEMBL2184899 0.83 MAPK1 (0.40) MAPK1CYP4F2CYP4A11KDM4ESMN1; SMN2
SCHEMBL19216523 0.82 SMN1; SMN2 (0.37) MAPK1CYP4F2CYP4A11KDM4ESMN1; SMN2
SCHEMBL5949120 0.82 POLB (0.38) MAPK1KDM4ESMN1; SMN2POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170283530-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF BEIJING LIHE TECH LTD (CN) 2017-10-05 US claimed
US-20160272733-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF BEIJING LIHE TECHNOLOGY LTD. (CN) 2016-09-22 US claimed
CN-103936892-A Solid catalyst component for olefin polymerization and catalyst BEIJIG LIHE ZHIXIN TECHNOLOGY LTD 2014-07-23 CN claimed
CN-103936893-A Catalyst component for olefin polymerization and catalyst BEIJIG LIHE ZHIXIN TECHNOLOGY LTD 2014-07-23 CN claimed
CN-103923237-A Catalyst component for olefin polymerization and application thereof BEIJING LIHE ZHIXIN TECHNOLOGY CO LTD 2014-07-16 CN claimed
CN-103923238-A Catalyst component for olefin polymerization and catalyst BEIJING LIHE ZHIXIN TECHNOLOGY CO LTD 2014-07-16 CN claimed
CN-103922928-A Ring substituted ether acid ester compound suitable for preparing olefin polymerization catalyst BEIJING LIHE ZHIXIN TECHNOLOGY CO LTD 2014-07-16 CN claimed
US-20190169328-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF RENQIU LIHE TECH LTD (CN) 2019-06-06 US disclosed
US-10208146-B2 Catalyst component for olefin polymerization and application thereof BEIJING LIHE TECHNOLOGY LTD. (CN) 2019-02-19 US disclosed
US-20170355792-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF RENQIU LIHE TECH LTD (CN) 2017-12-14 US disclosed
US-20170283530-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF BEIJING LIHE TECH LTD (CN) 2017-10-05 US disclosed
US-20160272733-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF BEIJING LIHE TECHNOLOGY LTD. (CN) 2016-09-22 US disclosed
CN-103936893-A Catalyst component for olefin polymerization and catalyst BEIJIG LIHE ZHIXIN TECHNOLOGY LTD 2014-07-23 CN disclosed
US-8048899-B2 Compounds which selectively modulate the CB2 receptor BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2011-11-01 US disclosed
CN-102164916-A Sulfonyl compounds that selectively modulate the CB2 receptor BOEHRINGER INGELHEIM INT 2011-08-24 CN disclosed
EP-2342200-A2 COMPOUNDS WHICH SELECTIVELY MODULATE THE CB2 RECEPTOR Boehringer Ingelheim International GmbH (DE) 2011-07-13 EP disclosed
US-20100081644-A1 Compounds Which Selectively Modulate The CB2 Receptor BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-04-01 US disclosed
US-20100081644-A1 Compounds Which Selectively Modulate The CB2 Receptor BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-04-01 US disclosed
WO-2010036630-A2 COMPOUNDS WHICH SELECTIVELY MODULATE THE CB2 RECEPTOR BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-04-01 WO disclosed
WO-2010036630-A2 COMPOUNDS WHICH SELECTIVELY MODULATE THE CB2 RECEPTOR BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-04-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100081644-A1 Compounds Which Selectively Modulate The CB2 Receptor CNR2, CNR1, OPRL1 MAPK1 1028/4885CYP4F2 1149/4885CYP4A11 469/4885
US-10208146-B2 Catalyst component for olefin polymerization and application thereof TEC, ETFA, TECR MAPK1 1257/4885CYP4F2 31/4885CYP4A11 171/4885
US-20190169328-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF COG2, GTF2I, POF1B MAPK1 1884/4885CYP4F2 148/4885CYP4A11 660/4885
US-20170283530-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF TEC, ETFA, TECR MAPK1 1257/4885CYP4F2 31/4885CYP4A11 171/4885
US-20170355792-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF COG2, COG7, COG4 MAPK1 3793/4885CYP4F2 251/4885CYP4A11 1061/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.