Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Ammonia Solution, Strong. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.78 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL29907 | 0.94 | MEN1 (0.88) | MEN1KMT2ACA5ACA5BTSHR | |
| Ammonia Solution, Strong SCHEMBL246568 | 0.94 | MEN1 (0.88) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL9743729 | 0.94 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Ammonia Solution, Strong SCHEMBL28282522 | 0.89 | — | — | |
| Ammonia Solution, Strong SCHEMBL28862965 | 0.89 | — | — | |
| Ammonia Solution, Strong SCHEMBL28322488 | 0.89 | — | — | |
| Water SCHEMBL19640167 | 0.89 | MEN1 (0.78) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL5330986 | 0.89 | MEN1 (0.78) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL3229361 | 0.89 | MEN1 (0.78) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL8512246 | 0.89 | MEN1 (0.78) | MEN1KMT2ACA5ACA5BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8778722-B2 | TFT substrate and method for producing TFT substrate | IDEMITSU KOSAN CO., LTD. (JP) | 2014-07-15 | — | — | US | disclosed |
| US-8263977-B2 | TFT substrate and TFT substrate manufacturing method | IDEMITSU KOSAN CO., LTD. (JP) | 2012-09-11 | — | — | US | disclosed |
| US-20120009725-A1 | TFT SUBSTRATE AND METHOD FOR PRODUCING TFT SUBSTRATE | INOUE KAZUYOSHI (JP) | 2012-01-12 | — | — | US | disclosed |
| US-20100283055-A1 | TFT SUBSTRATE AND TFT SUBSTRATE MANUFACTURING METHOD | INOUE KAZUYOSHI | 2010-11-11 | — | — | US | disclosed |