Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Ammonia Solution, Strong. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL28282522 | 0.89 | — | — | |
| Ammonia Solution, Strong SCHEMBL28862965 | 0.89 | — | — | |
| Ammonia Solution, Strong SCHEMBL28322488 | 0.89 | — | — | |
| Ammonia Solution, Strong SCHEMBL1690185 | 0.89 | MEN1 (0.78) | — | |
| SCHEMBL4278096 | 0.88 | — | — | |
| SCHEMBL6465752 | 0.88 | — | — | |
| Water SCHEMBL25211058 | 0.82 | — | — | |
| Ammonia Solution, Strong SCHEMBL7178587 | 0.82 | MEN1 (0.88) | — | |
| Ammonia Solution, Strong SCHEMBL2535374 | 0.82 | — | — | |
| Ammonia Solution, Strong SCHEMBL21611720 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8778722-B2 | TFT substrate and method for producing TFT substrate | IDEMITSU KOSAN CO., LTD. (JP) | 2014-07-15 | — | — | US | disclosed |
| US-8263977-B2 | TFT substrate and TFT substrate manufacturing method | IDEMITSU KOSAN CO., LTD. (JP) | 2012-09-11 | — | — | US | disclosed |
| US-20120009725-A1 | TFT SUBSTRATE AND METHOD FOR PRODUCING TFT SUBSTRATE | INOUE KAZUYOSHI (JP) | 2012-01-12 | — | — | US | disclosed |
| US-20100283055-A1 | TFT SUBSTRATE AND TFT SUBSTRATE MANUFACTURING METHOD | INOUE KAZUYOSHI | 2010-11-11 | — | — | US | disclosed |