Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 5/20 | 0.68 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.61 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.61 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.52 |
| ▸ | CHRNA5 | P30532 | 3/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13537172 | 0.85 | CYP11B2 (0.71) | CYP11B2CYP11B1CYP17A1CYP2A6ALDH1A1 | |
| SCHEMBL29809001 | 0.85 | CYP11B2 (0.71) | CYP11B2CYP11B1CYP17A1CYP2A6ALDH1A1 | |
| SCHEMBL2979806 | 0.85 | CYP11B2 (0.56) | CYP11B2CYP11B1CYP17A1ALDH1A1GRM5 | |
| SCHEMBL30346056 | 0.85 | CYP11B2 (0.56) | CYP11B2CYP11B1CYP17A1ALDH1A1GRM5 | |
| SCHEMBL2983844 | 0.84 | CYP11B2 (0.61) | CYP11B2CYP11B1CYP1A2CHRNB2CHRNA4 | |
| SCHEMBL17117024 | 0.83 | CYP11B2 (0.58) | CYP11B2CYP11B1CYP17A1MAP4K4 | |
| SCHEMBL6188982 | 0.81 | CYP11B2 (1.00) | CYP11B2CYP11B1CYP17A1CYP2A6ALDH1A1 | |
| Benzonitrile SCHEMBL29165371 | 0.81 | CYP11B2 (0.79) | CYP11B2CYP11B1CYP17A1CYP2A6ALDH1A1 | |
| SCHEMBL30726373 | 0.81 | CYP11B2 (0.56) | CYP11B2CYP11B1CYP2A6GRM5NPY5R | |
| SCHEMBL1651440 | 0.81 | CYP11B2 (0.56) | CYP11B2CYP11B1CYP2A6GRM5NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8951503-B2 | Optical determination of glucose utilizing boronic acid adducts | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-02-10 | — | — | US | disclosed |
| US-20130121925-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-05-16 | — | — | US | disclosed |
| US-8394357-B2 | Optical determination of glucose utilizing boronic acid adducts | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-03-12 | — | — | US | disclosed |
| US-20120009126-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-01-12 | — | — | US | disclosed |
| US-7968714-B2 | Optical determination of glucose utilizing boronic acid adducts | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-06-28 | — | — | US | disclosed |
| EP-2259061-A2 | Boronic acid derivatives | The Regents of The University of California (US) | 2010-12-08 | — | — | EP | disclosed |
| EP-1960779-B1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS-II | UNIV CALIFORNIA (US) | 2010-08-25 | — | — | EP | disclosed |
| US-7781591-B2 | Substituted 3-cyanopyridines as protein kinase inhibitors | WYETH LLC (US) | 2010-08-24 | — | — | US | disclosed |
| US-20090148344-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | SINGARAM BAKTHAN | 2009-06-11 | — | — | US | disclosed |
| US-20090148956-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | SINGARAM BAKTHAN | 2009-06-11 | — | — | US | disclosed |
| US-20090149656-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | SINGARAM BAKTHAN | 2009-06-11 | — | — | US | disclosed |
| US-7470420-B2 | Optical determination of glucose utilizing boronic acid adducts | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-12-30 | — | — | US | disclosed |
| EP-1960779-A2 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS-II | The Regents of the University of California (US) | 2008-08-27 | — | — | EP | disclosed |
| US-20070287708-A1 | Substituted 3-cyanopyridines as protein kinase inhibitors | WYETH LLC | 2007-12-13 | — | — | US | disclosed |
| WO-2007067743-A2 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS-II | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-06-14 | — | — | WO | disclosed |
| US-20060083688-A1 | Optical determination of glucose utilizing boronic acid adducts | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2006-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130121925-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | NISCH, FOSB, BLVRB | CYP11B2 856/4885CYP11B1 813/4885CYP17A1 2802/4885 |
| US-20090149656-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | NISCH, FOSB, BLVRB | CYP11B2 856/4885CYP11B1 813/4885CYP17A1 2802/4885 |
| US-20070287708-A1 | Substituted 3-cyanopyridines as protein kinase inhibitors | CNKSR1, MAP3K1, MAP3K7 | CYP11B2 2155/4885CYP11B1 1865/4885CYP17A1 2818/4885 |
| US-20120009126-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | NISCH, FOSB, BLVRB | CYP11B2 856/4885CYP11B1 813/4885CYP17A1 2802/4885 |
| US-20060083688-A1 | Optical determination of glucose utilizing boronic acid adducts | NISCH, FOSB, BLVRB | CYP11B2 856/4885CYP11B1 813/4885CYP17A1 2802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.