Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | G6PD | P11413 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL549183 | 0.90 | G6PD (0.45) | ALDH1A1MAPTHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL11631827 | 0.90 | KDM4E (0.50) | GPR3ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL17037096 | 0.89 | G6PD (0.44) | GPR3ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL16906027 | 0.89 | GPR3 (0.54) | GPR3ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL21116843 | 0.86 | APP (0.44) | GPR3ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL10053267 | 0.83 | G6PD (0.40) | GPR3ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL21692464 | 0.83 | LIMK1 (0.48) | GPR3ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL15158535 | 0.82 | ABCG2 (0.44) | GPR3ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL23625848 | 0.82 | STS (0.42) | GPR3ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL15318115 | 0.81 | ALDH1A1 (0.46) | GPR3ALDH1A1MAPTHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106397397-B | Diaryl and episulfide and selenides and its synthesis and application | 华东师范大学 | 2019-02-01 | — | — | CN | claimed |
| CN-105820098-B | Diaryl sulfide class compound and its synthetic method and application | 华东师范大学 | 2018-08-24 | — | — | CN | claimed |
| US-11005050-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-05-11 | — | — | US | disclosed |
| CN-106397397-B | Diaryl and episulfide and selenides and its synthesis and application | 华东师范大学 | 2019-02-01 | — | — | CN | disclosed |
| CN-105820098-B | Diaryl sulfide class compound and its synthetic method and application | 华东师范大学 | 2018-08-24 | — | — | CN | disclosed |
| EP-3094638-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2017-11-08 | — | — | EP | disclosed |
| US-20160365520-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2016-12-15 | — | — | US | disclosed |
| US-20160365520-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2016-12-15 | — | — | US | disclosed |
| WO-2015104045-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2015-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11005050-B2 | Metal complexes | SOD1, AP1M1, AP3M1 | GPR3 4376/4885ALDH1A1 3721/4885MAPT 1084/4885 |
| US-20160365520-A1 | METAL COMPLEXES | SOD1, AP1M1, AP3M1 | GPR3 4376/4885ALDH1A1 3721/4885MAPT 1084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.