Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | NPY4R | P50391 | 8/20 | 0.36 |
| ▸ | NPY1R | P25929 | 5/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 3/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.33 |
| ▸ | TLR2 | O60603 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | GNPAT | O15228 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5807639 | 0.89 | SIRT6 (0.44) | SIRT6SIRT1ACHENPY4RNPY1R | |
| SCHEMBL5807641 | 0.89 | SIRT6 (0.44) | SIRT6SIRT1ACHENPY4RNPY1R | |
| SCHEMBL5812133 | 0.86 | SIRT6 (0.43) | SIRT6SIRT1NPY4RNPY1RSIRT5 | |
| SCHEMBL5812127 | 0.86 | SIRT6 (0.43) | SIRT6SIRT1NPY4RNPY1RSIRT5 | |
| SCHEMBL2390736 | 0.86 | NPY4R (0.44) | SIRT6SIRT1NPY4RNPY1RSIRT5 | |
| SCHEMBL5807981 | 0.86 | NPY4R (0.44) | SIRT6SIRT1NPY4RNPY1RSIRT5 | |
| Hydrochloric Acid SCHEMBL11506342 | 0.85 | NPY4R (0.44) | SIRT6SIRT1NPY4RNPY1RSIRT5 | |
| SCHEMBL28406173 | 0.83 | SIRT6 (0.40) | SIRT6SIRT1NPY4RNPY1RSIRT5 | |
| SCHEMBL5814337 | 0.82 | SIRT6 (0.39) | SIRT6SIRT1NPY4RNPY1RSIRT5 | |
| SCHEMBL5814333 | 0.82 | SIRT6 (0.39) | SIRT6SIRT1NPY4RNPY1RSIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150197500-A1 | NO-RELEASING GUANIDINE-CHROMENE CONJUGATES | EUCLISES PHARMACEUTICALS INC (US) | 2015-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150197500-A1 | NO-RELEASING GUANIDINE-CHROMENE CONJUGATES | ARG1, ARGLU1, CGAS | SIRT6 1608/4885SIRT1 984/4885ACHE 1240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.