Phenol

Phenol

SCHEMBL16906342

C=C[Si](C)(C)c1ccccc1O.Oc1ccccc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.41
CA2 P00918 2/20 0.41
CA3 P07451 2/20 0.41
CA4 P22748 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
CA14 Q9ULX7 2/20 0.41
CA1 P00915 1/20 0.41
GLA P06280 1/20 0.41
CA9 Q16790 1/20 0.41
ESR1 P03372 4/20 0.38
ESR2 Q92731 4/20 0.38
ACHE P22303 3/20 0.33
ALDH1A1 P00352 2/20 0.32
CYP3A4 P08684 2/20 0.32
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.32
GMNN O75496 1/20 0.32
EGFR P00533 1/20 0.32
LMNA P02545 1/20 0.32
FYN P06241 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2558125 0.92 ALDH1A1 (0.38) CA12CA2CA3CA4TDP1
SCHEMBL3094174 0.77 NR1H2 (0.36) ALDH1A1NR1H2NR1H3
SCHEMBL4591829 0.77 ALDH1A1 (0.42) CA2TDP1CA1ESR1ESR2
Phenol SCHEMBL17048501 0.76 CA12 (0.52) CA12CA2CA3CA4TDP1
Phenol SCHEMBL7070848 0.70 CA12 (0.65) CA12CA2CA3CA4TDP1
Phenol SCHEMBL28603362 0.70 CA12 (0.65) CA12CA2CA3CA4TDP1
Phenol SCHEMBL258238 0.70 CA12 (0.65) CA12CA2CA3CA4TDP1
Phenol SCHEMBL1756183 0.70 CA12 (0.65) CA12CA2CA3CA4TDP1
Phenol SCHEMBL7077037 0.70 CA12 (0.65) CA12CA2CA3CA4TDP1
SCHEMBL9634722 0.70 TSHR (0.39) CA2TDP1CA1CA9ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015130652-A1 SYNTHESIS OF OLIGOMERIC DIVINYLDIALKYLSILANE CONTAINING COMPOSITIONS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2015-09-03 WO disclosed
US-9085692-B1 Synthesis of oligomeric divinyldialkylsilane containing compositions THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2015-07-21 US disclosed