Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2558125 | 0.83 | ALDH1A1 (0.38) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| Phenol SCHEMBL16906342 | 0.77 | CA12 (0.41) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL18604569 | 0.76 | ALDH1A1 (0.52) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL3094174 | 0.75 | NR1H2 (0.36) | ALDH1A1NR1H2NR1H3TSHR | |
| SCHEMBL9634722 | 0.68 | TSHR (0.39) | ALDH1A1CA1CA2TDP1CYP3A4 | |
| SCHEMBL21143008 | 0.68 | CYP2A6 (0.40) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL14586292 | 0.68 | ALDH1A1 (0.42) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| Pyrogallol SCHEMBL28249612 | 0.68 | ALDH1A1 (0.71) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL5772639 | 0.67 | NR1H2 (0.42) | TDP1TP53NR1H2NR1H3 | |
| SCHEMBL11358166 | 0.67 | ALDH1A1 (0.41) | ALDH1A1LMNAHPGDTP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7456298-B2 | Synthesis of acetonides from aryl silanes | GENENCOR INTERNATIONAL, INC. (US) | 2008-11-25 | — | — | US | disclosed |
| US-7456298-B2 | Synthesis of acetonides from aryl silanes | GENENCOR INTERNATIONAL, INC. (US) | 2008-11-25 | — | — | US | disclosed |
| US-7381830-B2 | Synthesis of cis-diols from aryl silanes | GENENCOR INTERNATIONAL, INC. (US) | 2008-06-03 | — | — | US | disclosed |
| US-7381830-B2 | Synthesis of cis-diols from aryl silanes | GENENCOR INTERNATIONAL, INC. (US) | 2008-06-03 | — | — | US | disclosed |
| EP-1534783-A4 | SYNTHESIS OF CIS-DIOLS FROM ARYL SILANES | DOW CORNING (US) | 2008-01-09 | — | — | EP | disclosed |
| US-20070213541-A1 | Synthesis of acetonides from aryl silanes | DOW CORNING CORPORATION | 2007-09-13 | — | — | US | disclosed |
| US-20070213541-A1 | Synthesis of acetonides from aryl silanes | DOW CORNING CORPORATION | 2007-09-13 | — | — | US | disclosed |
| US-20070213550-A1 | Synthesis of cis-diols from aryl silanes | DOW CORNING CORPORATION | 2007-09-13 | — | — | US | disclosed |
| US-20070213550-A1 | Synthesis of cis-diols from aryl silanes | DOW CORNING CORPORATION | 2007-09-13 | — | — | US | disclosed |
| US-7179932-B2 | Synthesis of cis-diols from aryl silanes | GENENCOR INTERNATIONAL, INC. (US) | 2007-02-20 | — | — | US | disclosed |
| US-7179932-B2 | Synthesis of cis-diols from aryl silanes | GENENCOR INTERNATIONAL, INC. (US) | 2007-02-20 | — | — | US | disclosed |
| EP-1534783-A2 | SYNTHESIS OF CIS-DIOLS FROM ARYL SILANES | Dow Corning Corporation (US) | 2005-06-01 | — | — | EP | disclosed |
| US-20040033574-A1 | Synthesis of cis-diols from aryl silanes | DOW CORNING CORPORATION | 2004-02-19 | — | — | US | disclosed |
| WO-2003102217-A2 | SYNTHESIS OF CIS-DIOLS FROM ARYL SILANES | DOW CORNING CORPORATION (US) | 2003-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213550-A1 | Synthesis of cis-diols from aryl silanes | CYP21A2, CYP11B2, CYP11B1 | ALDH1A1 135/4885LMNA 3972/4885HPGD 227/4885 |
| US-20070213541-A1 | Synthesis of acetonides from aryl silanes | CYP21A2, CYP11B1, CYP11B2 | ALDH1A1 191/4885LMNA 3705/4885HPGD 319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.